MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2.
<h4>Background</h4>Previous work has shown reduced expression levels of let-7 in lung tumors. But little is known about the expression or mechanisms of let-7a in prostate cancer. In this study, we used in vitro and in vivo approaches to investigate whether E2F2 and CCND2 are direct targe...
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Autores principales: | Qingchuan Dong, Ping Meng, Tao Wang, Weiwei Qin, Weijun Qin, Fuli Wang, Jianlin Yuan, Zhinan Chen, Angang Yang, He Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/812b9e64a52f4f2bba2515035729fe43 |
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