Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4
Neisseria meningitidis bacteria bind to host proteins CD147 and β2-adrenergic receptor on the surface of endothelial cells. Here, Maïssa et al. show that the two proteins interact with each other forming clusters that increase the binding strength of the bacteria to endothelial cells.
Guardado en:
Autores principales: | Nawal Maïssa, Valentina Covarelli, Sébastien Janel, Beatrice Durel, Nandi Simpson, Sandra C. Bernard, Liliana Pardo-Lopez, Haniaa Bouzinba-Ségard, Camille Faure, Mark G.H. Scott, Mathieu Coureuil, Philippe C. Morand, Frank Lafont, Xavier Nassif, Stefano Marullo, Sandrine Bourdoulous |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/812ccd1878054e24ab2fafea122fa20e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Structure of the Neisseria meningitidis Type IV pilus
por: Subramania Kolappan, et al.
Publicado: (2016) -
Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization
por: Elena Capel, et al.
Publicado: (2016) -
Molecular characteristics of Neisseria meningitidis in Qatar
por: Manal Mahmoud Hamed, et al.
Publicado: (2021) -
HAMLET binding to α-actinin facilitates tumor cell detachment.
por: Maria Trulsson, et al.
Publicado: (2011) -
Airway Mucus Restricts <named-content content-type="genus-species">Neisseria meningitidis</named-content> Away from Nasopharyngeal Epithelial Cells and Protects the Mucosa from Inflammation
por: Mathilde Audry, et al.
Publicado: (2019)