Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy

Yang Yang,1,&ast; Chenyang Li,2,&ast; Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Depa...

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Autores principales:	Yang Y, Li C, Zhao L, Li J, Han F, Xiao F
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	narcolepsy adolescents depression symptoms hypnagogic/hypnopompic hallucination Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
Acceso en línea:	https://doaj.org/article/8137b9026a8e4d7bb79755a8c0be792d
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spelling	oai:doaj.org-article:8137b9026a8e4d7bb79755a8c0be792d2021-12-02T15:24:23ZFactors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy1179-1608https://doaj.org/article/8137b9026a8e4d7bb79755a8c0be792d2021-07-01T00:00:00Zhttps://www.dovepress.com/factors-associated-with-depression-and-sub-dimension-symptoms-in-adole-peer-reviewed-fulltext-article-NSShttps://doaj.org/toc/1179-1608Yang Yang,1,&ast; Chenyang Li,2,&ast; Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China; 3Department of General Internal Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fang Han; Fulong XiaoPeking University People’s Hospital, No. 11, South Avenue, Beijing, People’s Republic of ChinaEmail hanfang1@hotmail.com; xiaofulong1681@163.comObjective: We evaluate the association between depression symptoms, clinical features (disease onset-age, disease duration, sleep-related hallucination), sleepiness, and polysomnography parameters in adolescent narcolepsy type 1 patients.Methods: Eighty-three adolescent narcolepsy type 1 patients were involved in this cross-sectional study. Patients completed questionnaires evaluating depression symptoms (Center for Epidemiologic Studies Depression Scale) and sleepiness (Epworth Sleepiness Scale). Parameters from polysomnography and multiple sleep latency test were also collected.Results: Patients with depression symptoms (62.7%) have later disease onset-age. Depression symptoms were associated with sleep-related hallucination (OR = 2.75). Six independent variables were associated with sub-dimensional depression symptoms, including sleep latency, sleep efficiency, sleep-related hallucination, Epworth sleepiness scale, disease duration, and disease onset-age.Conclusion: Sleep-related hallucination is associated with total depression symptoms in adolescent narcolepsy. Subjective sleepiness is associated with depressed affect, somatic symptoms, and interpersonal problems. Lower sleep efficiency is associated with a lack of positive affect.Keywords: narcolepsy, adolescents, depression symptoms, hypnagogic/hypnopompic hallucinationYang YLi CZhao LLi JHan FXiao FDove Medical Pressarticlenarcolepsyadolescentsdepression symptomshypnagogic/hypnopompic hallucinationPsychiatryRC435-571Neurophysiology and neuropsychologyQP351-495ENNature and Science of Sleep, Vol Volume 13, Pp 1075-1082 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	narcolepsy adolescents depression symptoms hypnagogic/hypnopompic hallucination Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
spellingShingle	narcolepsy adolescents depression symptoms hypnagogic/hypnopompic hallucination Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 Yang Y Li C Zhao L Li J Han F Xiao F Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
description	Yang Yang,1,&ast; Chenyang Li,2,&ast; Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China; 3Department of General Internal Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fang Han; Fulong XiaoPeking University People’s Hospital, No. 11, South Avenue, Beijing, People’s Republic of ChinaEmail hanfang1@hotmail.com; xiaofulong1681@163.comObjective: We evaluate the association between depression symptoms, clinical features (disease onset-age, disease duration, sleep-related hallucination), sleepiness, and polysomnography parameters in adolescent narcolepsy type 1 patients.Methods: Eighty-three adolescent narcolepsy type 1 patients were involved in this cross-sectional study. Patients completed questionnaires evaluating depression symptoms (Center for Epidemiologic Studies Depression Scale) and sleepiness (Epworth Sleepiness Scale). Parameters from polysomnography and multiple sleep latency test were also collected.Results: Patients with depression symptoms (62.7%) have later disease onset-age. Depression symptoms were associated with sleep-related hallucination (OR = 2.75). Six independent variables were associated with sub-dimensional depression symptoms, including sleep latency, sleep efficiency, sleep-related hallucination, Epworth sleepiness scale, disease duration, and disease onset-age.Conclusion: Sleep-related hallucination is associated with total depression symptoms in adolescent narcolepsy. Subjective sleepiness is associated with depressed affect, somatic symptoms, and interpersonal problems. Lower sleep efficiency is associated with a lack of positive affect.Keywords: narcolepsy, adolescents, depression symptoms, hypnagogic/hypnopompic hallucination
format	article
author	Yang Y Li C Zhao L Li J Han F Xiao F
author_facet	Yang Y Li C Zhao L Li J Han F Xiao F
author_sort	Yang Y
title	Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
title_short	Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
title_full	Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
title_fullStr	Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
title_full_unstemmed	Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
title_sort	factors associated with depression and sub-dimension symptoms in adolescent narcolepsy
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/8137b9026a8e4d7bb79755a8c0be792d
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Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy

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