Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes

N 6-methyladenosine (m6A) and N 6,2′-O-dimethyladenosine (m6Am) are eukaryotic mRNA modifications. Here the authors develop m6A-Crosslinking-Exonuclease-sequencing to map quantitative methylome changes at single-base-resolution after individually knocking out each known methyltransferase or demethyl...

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Autores principales:	Casslynn W. Q. Koh, Yeek Teck Goh, W. S. Sho Goh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8138bf4391664fa6ada76014c0a5fdcb
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spelling	oai:doaj.org-article:8138bf4391664fa6ada76014c0a5fdcb2021-12-02T15:35:55ZAtlas of quantitative single-base-resolution N 6-methyl-adenine methylomes10.1038/s41467-019-13561-z2041-1723https://doaj.org/article/8138bf4391664fa6ada76014c0a5fdcb2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13561-zhttps://doaj.org/toc/2041-1723N 6-methyladenosine (m6A) and N 6,2′-O-dimethyladenosine (m6Am) are eukaryotic mRNA modifications. Here the authors develop m6A-Crosslinking-Exonuclease-sequencing to map quantitative methylome changes at single-base-resolution after individually knocking out each known methyltransferase or demethylase.Casslynn W. Q. KohYeek Teck GohW. S. Sho GohNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Casslynn W. Q. Koh Yeek Teck Goh W. S. Sho Goh Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
description	N 6-methyladenosine (m6A) and N 6,2′-O-dimethyladenosine (m6Am) are eukaryotic mRNA modifications. Here the authors develop m6A-Crosslinking-Exonuclease-sequencing to map quantitative methylome changes at single-base-resolution after individually knocking out each known methyltransferase or demethylase.
format	article
author	Casslynn W. Q. Koh Yeek Teck Goh W. S. Sho Goh
author_facet	Casslynn W. Q. Koh Yeek Teck Goh W. S. Sho Goh
author_sort	Casslynn W. Q. Koh
title	Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
title_short	Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
title_full	Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
title_fullStr	Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
title_full_unstemmed	Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes
title_sort	atlas of quantitative single-base-resolution n 6-methyl-adenine methylomes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8138bf4391664fa6ada76014c0a5fdcb
work_keys_str_mv	AT casslynnwqkoh atlasofquantitativesinglebaseresolutionn6methyladeninemethylomes AT yeekteckgoh atlasofquantitativesinglebaseresolutionn6methyladeninemethylomes AT wsshogoh atlasofquantitativesinglebaseresolutionn6methyladeninemethylomes
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Atlas of quantitative single-base-resolution N 6-methyl-adenine methylomes

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