Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci.

Altered mitochondrial DNA (mtDNA) levels have been associated with common diseases in humans. We investigated the genetic mechanism that controls mtDNA levels using genome-wide linkage analyses in families from the Genetic Analysis of Idiopathic Thrombophilia Project (GAIT). We measure mtDNA levels...

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Bibliographic Details
Main Authors: Sonia López, Alfonso Buil, Juan Carlos Souto, Jordi Casademont, John Blangero, Angel Martinez-Perez, Jordi Fontcuberta, Mark Lathrop, Laura Almasy, Jose Manuel Soria
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/813c9936137a49e9ab8a79252a269ab3
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