The relationship between the level of vitamin D and ruptured intracranial aneurysms

Abstract The purpose of our research is to explore whether vitamin D levels were associated with the rupture of intracranial aneurysms. In this retrospective study, 105 patients diagnosed with ruptured intracranial aneurysms (RIAs) and 185 patients diagnosed with unruptured intracranial aneurysms (U...

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Autores principales:	Sen Wei, Xin Yuan, Feng Fan, Xin‑bin Guo, Sheng Guan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/813d9ab903864cc2863973f08a183ec2
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spelling	oai:doaj.org-article:813d9ab903864cc2863973f08a183ec22021-12-02T15:02:40ZThe relationship between the level of vitamin D and ruptured intracranial aneurysms10.1038/s41598-021-90760-z2045-2322https://doaj.org/article/813d9ab903864cc2863973f08a183ec22021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90760-zhttps://doaj.org/toc/2045-2322Abstract The purpose of our research is to explore whether vitamin D levels were associated with the rupture of intracranial aneurysms. In this retrospective study, 105 patients diagnosed with ruptured intracranial aneurysms (RIAs) and 185 patients diagnosed with unruptured intracranial aneurysms (UIAs) at The First Affiliated Hospital of Zhengzhou University were recruited from September 2019 to September 2020. Patients’ demographic and clinical information, including vitamin D levels, were recorded and compared. Univariate analysis showed that patients with UIAs had higher vitamin D levels than RIAs (p = 0.019). In addition, there were significant differences in aneurysm location (p < 0.001), aspirin use (p = 0.001), and comorbid diabetes mellitus (p = 0.037) between patients with UIAs and RIAs. Binary logistic regression analysis showed that the level of vitamin D was independently associated with RIAs [odds ratio (OR) 0.960; 95% confidence intervals (CI), 0.926–0.996, p = 0.028].Sen WeiXin YuanFeng FanXin‑bin GuoSheng GuanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sen Wei Xin Yuan Feng Fan Xin‑bin Guo Sheng Guan The relationship between the level of vitamin D and ruptured intracranial aneurysms
description	Abstract The purpose of our research is to explore whether vitamin D levels were associated with the rupture of intracranial aneurysms. In this retrospective study, 105 patients diagnosed with ruptured intracranial aneurysms (RIAs) and 185 patients diagnosed with unruptured intracranial aneurysms (UIAs) at The First Affiliated Hospital of Zhengzhou University were recruited from September 2019 to September 2020. Patients’ demographic and clinical information, including vitamin D levels, were recorded and compared. Univariate analysis showed that patients with UIAs had higher vitamin D levels than RIAs (p = 0.019). In addition, there were significant differences in aneurysm location (p < 0.001), aspirin use (p = 0.001), and comorbid diabetes mellitus (p = 0.037) between patients with UIAs and RIAs. Binary logistic regression analysis showed that the level of vitamin D was independently associated with RIAs [odds ratio (OR) 0.960; 95% confidence intervals (CI), 0.926–0.996, p = 0.028].
format	article
author	Sen Wei Xin Yuan Feng Fan Xin‑bin Guo Sheng Guan
author_facet	Sen Wei Xin Yuan Feng Fan Xin‑bin Guo Sheng Guan
author_sort	Sen Wei
title	The relationship between the level of vitamin D and ruptured intracranial aneurysms
title_short	The relationship between the level of vitamin D and ruptured intracranial aneurysms
title_full	The relationship between the level of vitamin D and ruptured intracranial aneurysms
title_fullStr	The relationship between the level of vitamin D and ruptured intracranial aneurysms
title_full_unstemmed	The relationship between the level of vitamin D and ruptured intracranial aneurysms
title_sort	relationship between the level of vitamin d and ruptured intracranial aneurysms
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/813d9ab903864cc2863973f08a183ec2
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The relationship between the level of vitamin D and ruptured intracranial aneurysms

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