Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of drugs. The present research is to develop piperine self-nanoemulsifying drug delivery system (PE-SNEDDS) using glyceryl monolinoleate (GML), poloxamer 188, and t...

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Autores principales: Ameeduzzafar Zafar, Syed Sarim Imam, Nabil K. Alruwaili, Omar Awad Alsaidan, Mohammed H. Elkomy, Mohammed M. Ghoneim, Sultan Alshehri, Ahmed Mahmoud Abdelhaleem Ali, Khalid Saad Alharbi, Mohd Yasir, Kaveripakkam M. Noorulla, Sami I. Alzarea, Abdullah S. Alanazi
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
oral delivery
piperine
solid self nanoemusifying
antimicrobial activity
antihypertensive activity
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/8140c9b4db6f448683e47472324060ea
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