Stimulated Expression of CXCL12 in Adrenocortical Carcinoma by the PPARgamma Ligand Rosiglitazone Impairs Cancer Progression

Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis when metastatic and scarce treatment options in the advanced stages. In solid tumors, the chemokine CXCL12/CXCR4 axis is involved in the metastatic process. We demonstrated that the human adrenocortex expressed CXCL12 and its co...

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Auteurs principaux:	Giulia Cantini, Laura Fei, Letizia Canu, Elena Lazzeri, Mariangela Sottili, Michela Francalanci, Maria Lucia Angelotti, Giuseppina De Filpo, Tonino Ercolino, Stefania Gelmini, Monica Mangoni, Gabriella Nesi, Constanze Hantel, Massimo Mannelli, Mario Maggi, Michaela Luconi
Format:	article
Langue:	EN
Publié:	MDPI AG 2021
Sujets:	chemokines rare cancers ACC xenograft cancer models anti-cancer therapy thiazolidinediones Medicine R
Accès en ligne:	https://doaj.org/article/814e9f34ad2c4aa8be3f47d9b86d050b
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Stimulated Expression of CXCL12 in Adrenocortical Carcinoma by the PPARgamma Ligand Rosiglitazone Impairs Cancer Progression

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