Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease

Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbial functions and the onset of Crohn’s disease.

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Detalles Bibliográficos
Autores principales: Xu Zhang, Zhibin Ning, Janice Mayne, Yidai Yang, Shelley A. Deeke, Krystal Walker, Charles L. Farnsworth, Matthew P. Stokes, Jean-François Couture, David Mack, Alain Stintzi, Daniel Figeys
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8156c241c00f4392889e3f4fe586f531
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Sumario:Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbial functions and the onset of Crohn’s disease.