Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease

Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbial functions and the onset of Crohn’s disease.

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Autores principales: Xu Zhang, Zhibin Ning, Janice Mayne, Yidai Yang, Shelley A. Deeke, Krystal Walker, Charles L. Farnsworth, Matthew P. Stokes, Jean-François Couture, David Mack, Alain Stintzi, Daniel Figeys
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8156c241c00f4392889e3f4fe586f531
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spelling oai:doaj.org-article:8156c241c00f4392889e3f4fe586f5312021-12-02T15:10:51ZWidespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease10.1038/s41467-020-17916-92041-1723https://doaj.org/article/8156c241c00f4392889e3f4fe586f5312020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17916-9https://doaj.org/toc/2041-1723Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbial functions and the onset of Crohn’s disease.Xu ZhangZhibin NingJanice MayneYidai YangShelley A. DeekeKrystal WalkerCharles L. FarnsworthMatthew P. StokesJean-François CoutureDavid MackAlain StintziDaniel FigeysNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xu Zhang
Zhibin Ning
Janice Mayne
Yidai Yang
Shelley A. Deeke
Krystal Walker
Charles L. Farnsworth
Matthew P. Stokes
Jean-François Couture
David Mack
Alain Stintzi
Daniel Figeys
Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
description Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbial functions and the onset of Crohn’s disease.
format article
author Xu Zhang
Zhibin Ning
Janice Mayne
Yidai Yang
Shelley A. Deeke
Krystal Walker
Charles L. Farnsworth
Matthew P. Stokes
Jean-François Couture
David Mack
Alain Stintzi
Daniel Figeys
author_facet Xu Zhang
Zhibin Ning
Janice Mayne
Yidai Yang
Shelley A. Deeke
Krystal Walker
Charles L. Farnsworth
Matthew P. Stokes
Jean-François Couture
David Mack
Alain Stintzi
Daniel Figeys
author_sort Xu Zhang
title Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
title_short Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
title_full Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
title_fullStr Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
title_full_unstemmed Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
title_sort widespread protein lysine acetylation in gut microbiome and its alterations in patients with crohn’s disease
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8156c241c00f4392889e3f4fe586f531
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