Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways

Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance o...

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Autores principales: William C. DeLoache, Zachary N. Russ, John E. Dueber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8162265359a841f2a8a7cae3523cd840
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spelling oai:doaj.org-article:8162265359a841f2a8a7cae3523cd8402021-12-02T16:49:58ZTowards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways10.1038/ncomms111522041-1723https://doaj.org/article/8162265359a841f2a8a7cae3523cd8402016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11152https://doaj.org/toc/2041-1723Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance of a model pathway.William C. DeLoacheZachary N. RussJohn E. DueberNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
William C. DeLoache
Zachary N. Russ
John E. Dueber
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
description Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance of a model pathway.
format article
author William C. DeLoache
Zachary N. Russ
John E. Dueber
author_facet William C. DeLoache
Zachary N. Russ
John E. Dueber
author_sort William C. DeLoache
title Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
title_short Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
title_full Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
title_fullStr Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
title_full_unstemmed Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
title_sort towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8162265359a841f2a8a7cae3523cd840
work_keys_str_mv AT williamcdeloache towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways
AT zacharynruss towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways
AT johnedueber towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways
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