Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance o...
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Nature Portfolio
2016
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oai:doaj.org-article:8162265359a841f2a8a7cae3523cd8402021-12-02T16:49:58ZTowards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways10.1038/ncomms111522041-1723https://doaj.org/article/8162265359a841f2a8a7cae3523cd8402016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11152https://doaj.org/toc/2041-1723Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance of a model pathway.William C. DeLoacheZachary N. RussJohn E. DueberNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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Science Q William C. DeLoache Zachary N. Russ John E. Dueber Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
description |
Compartmentalization of enzymes into cellular organelles is a promising strategy for improving pathway efficiency. Here, the authors use a high-throughput assay to identify enhanced peroxisomal targeting signals in yeast, and study the effects of peroxisomal compartmentalization on the performance of a model pathway. |
format |
article |
author |
William C. DeLoache Zachary N. Russ John E. Dueber |
author_facet |
William C. DeLoache Zachary N. Russ John E. Dueber |
author_sort |
William C. DeLoache |
title |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
title_short |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
title_full |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
title_fullStr |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
title_full_unstemmed |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
title_sort |
towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/8162265359a841f2a8a7cae3523cd840 |
work_keys_str_mv |
AT williamcdeloache towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways AT zacharynruss towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways AT johnedueber towardsrepurposingtheyeastperoxisomeforcompartmentalizingheterologousmetabolicpathways |
_version_ |
1718383167721701376 |