Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK

Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK

The chaperone HYPK regulates the human N-terminal acetyltransferase E (NatE) complex, but the mechanism is not fully understood. Here, the authors study the interplay of NatE and HYPK by cryo-EM and biochemical approaches, providing insights into the molecular basis of N-terminal acetylation of huma...

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Autores principales: Sunbin Deng, Nina McTiernan, Xuepeng Wei, Thomas Arnesen, Ronen Marmorstein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/81657bc1bec14c11ac8cd119b0aa1960
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