Mad1's ability to interact with Mad2 is essential to regulate and monitor meiotic synapsis in C. elegans.
Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle checkpoint components, Mad1 and Mad2, and Pairing Centers (PCs), cis-acting loci that interac...
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Main Authors: | , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/8172bf6758db40e384b043d3d26addb4 |
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