Mad1's ability to interact with Mad2 is essential to regulate and monitor meiotic synapsis in C. elegans.

Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle checkpoint components, Mad1 and Mad2, and Pairing Centers (PCs), cis-acting loci that interac...

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Bibliographic Details
Main Authors: Alice Devigne, Needhi Bhalla
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/8172bf6758db40e384b043d3d26addb4
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