CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
Abstract. We studied some effects of a biologically active food additive (BAFA) «DNAaC» which contains DNA from salmon soft roe and vitamin C as active substances. This BAFA was investigated as a complementary remedy during radiation therapy of women with breast cancer (BrC), with respect to dynamic...
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
SPb RAACI
2014
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/81759663e6384d709e1b9c0dcd7547af |
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| Sumario: | Abstract. We studied some effects of a biologically active food additive (BAFA) «DNAaC» which contains DNA from salmon soft roe and vitamin C as active substances. This BAFA was investigated as a complementary remedy during radiation therapy of women with breast cancer (BrC), with respect to dynamics and levels blood serum cytokines, i.e., early hematopoietic factors (IL-3, GM-CSF, TNFa), and balance of marker cytokines for Th1- and Th2-response (IFNγ, IL-10). It was shown that «DNAaC» has modulating effect on secretion of all investigated cytokines. There was, however, a higher and statistically valid corrective effect upon GM-CSF, along with increase of initially low IFNγ and TNFa concentrations, and reduction of initially high IL-10 levels. Hence, «DNAaC» contributes to improvement of cell-mediated immune deficiency, stabilization of hematopoietic system, and brings about tolerance to basic treatment approaches in oncological diseases. |
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