CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C

Abstract. We studied some effects of a biologically active food additive (BAFA) «DNAaC» which contains DNA from salmon soft roe and vitamin C as active substances. This BAFA was investigated as a complementary remedy during radiation therapy of women with breast cancer (BrC), with respect to dynamic...

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Autor principal:	L. N. Fedyanina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	cytokines breast cancer biologically active food additive Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/81759663e6384d709e1b9c0dcd7547af
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spelling	oai:doaj.org-article:81759663e6384d709e1b9c0dcd7547af2021-11-18T08:03:39ZCYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C1563-06252313-741X10.15789/1563-0625-2007-4-5-509-512https://doaj.org/article/81759663e6384d709e1b9c0dcd7547af2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/231https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We studied some effects of a biologically active food additive (BAFA) «DNAaC» which contains DNA from salmon soft roe and vitamin C as active substances. This BAFA was investigated as a complementary remedy during radiation therapy of women with breast cancer (BrC), with respect to dynamics and levels blood serum cytokines, i.e., early hematopoietic factors (IL-3, GM-CSF, TNFa), and balance of marker cytokines for Th1- and Th2-response (IFNγ, IL-10). It was shown that «DNAaC» has modulating effect on secretion of all investigated cytokines. There was, however, a higher and statistically valid corrective effect upon GM-CSF, along with increase of initially low IFNγ and TNFa concentrations, and reduction of initially high IL-10 levels. Hence, «DNAaC» contributes to improvement of cell-mediated immune deficiency, stabilization of hematopoietic system, and brings about tolerance to basic treatment approaches in oncological diseases.L. N. FedyaninaSPb RAACIarticlecytokinesbreast cancerbiologically active food additiveImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 4-5, Pp 509-512 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	cytokines breast cancer biologically active food additive Immunologic diseases. Allergy RC581-607
spellingShingle	cytokines breast cancer biologically active food additive Immunologic diseases. Allergy RC581-607 L. N. Fedyanina CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
description	Abstract. We studied some effects of a biologically active food additive (BAFA) «DNAaC» which contains DNA from salmon soft roe and vitamin C as active substances. This BAFA was investigated as a complementary remedy during radiation therapy of women with breast cancer (BrC), with respect to dynamics and levels blood serum cytokines, i.e., early hematopoietic factors (IL-3, GM-CSF, TNFa), and balance of marker cytokines for Th1- and Th2-response (IFNγ, IL-10). It was shown that «DNAaC» has modulating effect on secretion of all investigated cytokines. There was, however, a higher and statistically valid corrective effect upon GM-CSF, along with increase of initially low IFNγ and TNFa concentrations, and reduction of initially high IL-10 levels. Hence, «DNAaC» contributes to improvement of cell-mediated immune deficiency, stabilization of hematopoietic system, and brings about tolerance to basic treatment approaches in oncological diseases.
format	article
author	L. N. Fedyanina
author_facet	L. N. Fedyanina
author_sort	L. N. Fedyanina
title	CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
title_short	CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
title_full	CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
title_fullStr	CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
title_full_unstemmed	CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C
title_sort	cytokines in breast cancer patients during radiation therapy: complementary effects of biologically active food additive containing salmon soft roe and vitamin c
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/81759663e6384d709e1b9c0dcd7547af
work_keys_str_mv	AT lnfedyanina cytokinesinbreastcancerpatientsduringradiationtherapycomplementaryeffectsofbiologicallyactivefoodadditivecontainingsalmonsoftroeandvitaminc
_version_	1718422554453999616

CYTOKINES IN BREAST CANCER PATIENTS DURING RADIATION THERAPY: COMPLEMENTARY EFFECTS OF BIOLOGICALLY ACTIVE FOOD ADDITIVE CONTAINING SALMON SOFT ROE AND VITAMIN C

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