Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study

Benchalak Maneeton,1 Narong Maneeton,1 Worawit Louthrenoo2 1Department of Psychiatry, 2Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Objective: The purpose of this study was to estimate the prevalence and examine the predictors of depression in patients wit...

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Autores principales:	Maneeton B, Maneeton N, Louthrenoo W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/81848f0ae6054d30b64a82a45827466a
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spelling	oai:doaj.org-article:81848f0ae6054d30b64a82a45827466a2021-12-02T02:34:16ZPrevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study1176-63281178-2021https://doaj.org/article/81848f0ae6054d30b64a82a45827466a2013-06-01T00:00:00Zhttp://www.dovepress.com/prevalence-and-predictors-of-depression-in-patients-with-systemic-lupu-a13242https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Benchalak Maneeton,1 Narong Maneeton,1 Worawit Louthrenoo2 1Department of Psychiatry, 2Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Objective: The purpose of this study was to estimate the prevalence and examine the predictors of depression in patients with systemic lupus erythematosus (SLE). Methods: This cross-sectional study was conducted in the rheumatology clinic of a university hospital. All SLE patients that met the revised American College of Rheumatology (ACR) classification were included in the study. Sociodemographic data and medications were recorded. Disease activity for SLE was assessed with the Mexican-SLE Disease Activity Index (Mex-SLEDAI). All subjects were screened for anxiety and depression by using the Hamilton Anxiety Rating Scale (HAM-A) and the 17-item version of the Hamilton Depression Rating Scale (HAM-D17). Multiple linear regression analyses were used to determine predictors of depressive disorder. Results: A total of 62 SLE (61 females and 1 male) patients participated in the study. Based on HAM-D17 and HAM-A, rates of depression and anxiety in SLE patients were 45.2% and 37.1%, respectively. The multiple linear regression analysis revealed that HAM-A score and younger age were significant predictors of depression in SLE patients. Conclusion: The findings suggest that depression and anxiety are common in SLE patients. In addition, higher levels of anxiety and a younger age may increase the risk of depression. Because of the small sample size, further studies should be conducted to confirm these results. Keywords: systemic lupus erythematosus, depression, anxiety disorderManeeton BManeeton NLouthrenoo WDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 799-804 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Maneeton B Maneeton N Louthrenoo W Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
description	Benchalak Maneeton,1 Narong Maneeton,1 Worawit Louthrenoo2 1Department of Psychiatry, 2Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Objective: The purpose of this study was to estimate the prevalence and examine the predictors of depression in patients with systemic lupus erythematosus (SLE). Methods: This cross-sectional study was conducted in the rheumatology clinic of a university hospital. All SLE patients that met the revised American College of Rheumatology (ACR) classification were included in the study. Sociodemographic data and medications were recorded. Disease activity for SLE was assessed with the Mexican-SLE Disease Activity Index (Mex-SLEDAI). All subjects were screened for anxiety and depression by using the Hamilton Anxiety Rating Scale (HAM-A) and the 17-item version of the Hamilton Depression Rating Scale (HAM-D17). Multiple linear regression analyses were used to determine predictors of depressive disorder. Results: A total of 62 SLE (61 females and 1 male) patients participated in the study. Based on HAM-D17 and HAM-A, rates of depression and anxiety in SLE patients were 45.2% and 37.1%, respectively. The multiple linear regression analysis revealed that HAM-A score and younger age were significant predictors of depression in SLE patients. Conclusion: The findings suggest that depression and anxiety are common in SLE patients. In addition, higher levels of anxiety and a younger age may increase the risk of depression. Because of the small sample size, further studies should be conducted to confirm these results. Keywords: systemic lupus erythematosus, depression, anxiety disorder
format	article
author	Maneeton B Maneeton N Louthrenoo W
author_facet	Maneeton B Maneeton N Louthrenoo W
author_sort	Maneeton B
title	Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
title_short	Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
title_full	Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
title_fullStr	Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
title_full_unstemmed	Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
title_sort	prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/81848f0ae6054d30b64a82a45827466a
work_keys_str_mv	AT maneetonb prevalenceandpredictorsofdepressioninpatientswithsystemiclupuserythematosusacrosssectionalstudy AT maneetonn prevalenceandpredictorsofdepressioninpatientswithsystemiclupuserythematosusacrosssectionalstudy AT louthrenoow prevalenceandpredictorsofdepressioninpatientswithsystemiclupuserythematosusacrosssectionalstudy
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Prevalence and predictors of depression in patients with systemic lupus erythematosus: a cross-sectional study

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