Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates

At the end of 2019, the new coronavirus caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly raged, bringing a severe public health crisis to the world. It is urgent to discover suitable drugs and treatment regimens against this coronavirus disease 2019 (COVID-19) and rela...

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Autores principales:	Qian Wang, Zhenming Liu
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019 Surface plasmon resonance technology Invasion mode Antiviral drug development Pharmacy and materia medica RS1-441 Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/818825880f674aab9df20cf773ac84dc
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spelling	oai:doaj.org-article:818825880f674aab9df20cf773ac84dc2021-12-03T04:01:35ZRecent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates2772-417410.1016/j.ejmcr.2021.100003https://doaj.org/article/818825880f674aab9df20cf773ac84dc2021-07-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2772417421000030https://doaj.org/toc/2772-4174At the end of 2019, the new coronavirus caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly raged, bringing a severe public health crisis to the world. It is urgent to discover suitable drugs and treatment regimens against this coronavirus disease 2019 (COVID-19) and related diseases. Based on the previous knowledge and experience in treating similar diseases, researchers have come up with hundreds of possible drug candidates in the shortest possible time. Based on surface plasmon resonance (SPR) technology, this review summarized the application of SPR technology in COVID-19 research from four aspects: the invasion mode of SARS-CoV-2 into host cells, antibody drug candidates for the treatment of COVID-19, small molecule drug repurposing and vaccines for COVID-19. SPR technology has gradually become a powerful tool to study the interaction between drugs and targets due to its high efficiency, automation, labeling-free and high data resolution. The use of SPR technology can not only obtain the affinity data between drugs and targets, but also clarify the binding sites and mechanisms of drugs. We hope that this review can provide a reference for the subsequent application of SPR technology in antiviral drug development.Qian WangZhenming LiuElsevierarticleSevere acute respiratory syndrome coronavirus 2Coronavirus disease 2019Surface plasmon resonance technologyInvasion modeAntiviral drug developmentPharmacy and materia medicaRS1-441Other systems of medicineRZ201-999ENEuropean Journal of Medicinal Chemistry Reports, Vol 1, Iss , Pp 100003- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019 Surface plasmon resonance technology Invasion mode Antiviral drug development Pharmacy and materia medica RS1-441 Other systems of medicine RZ201-999
spellingShingle	Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019 Surface plasmon resonance technology Invasion mode Antiviral drug development Pharmacy and materia medica RS1-441 Other systems of medicine RZ201-999 Qian Wang Zhenming Liu Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
description	At the end of 2019, the new coronavirus caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly raged, bringing a severe public health crisis to the world. It is urgent to discover suitable drugs and treatment regimens against this coronavirus disease 2019 (COVID-19) and related diseases. Based on the previous knowledge and experience in treating similar diseases, researchers have come up with hundreds of possible drug candidates in the shortest possible time. Based on surface plasmon resonance (SPR) technology, this review summarized the application of SPR technology in COVID-19 research from four aspects: the invasion mode of SARS-CoV-2 into host cells, antibody drug candidates for the treatment of COVID-19, small molecule drug repurposing and vaccines for COVID-19. SPR technology has gradually become a powerful tool to study the interaction between drugs and targets due to its high efficiency, automation, labeling-free and high data resolution. The use of SPR technology can not only obtain the affinity data between drugs and targets, but also clarify the binding sites and mechanisms of drugs. We hope that this review can provide a reference for the subsequent application of SPR technology in antiviral drug development.
format	article
author	Qian Wang Zhenming Liu
author_facet	Qian Wang Zhenming Liu
author_sort	Qian Wang
title	Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
title_short	Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
title_full	Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
title_fullStr	Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
title_full_unstemmed	Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
title_sort	recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/818825880f674aab9df20cf773ac84dc
work_keys_str_mv	AT qianwang recentprogressofsurfaceplasmonresonanceinthedevelopmentofcoronavirusdisease2019drugcandidates AT zhenmingliu recentprogressofsurfaceplasmonresonanceinthedevelopmentofcoronavirusdisease2019drugcandidates
_version_	1718373941282603008

Recent progress of surface plasmon resonance in the development of coronavirus disease-2019 drug candidates

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