C-Terminal Farnesylation of UCH-L1 Plays a Role in Transport of Epstein-Barr Virus Primary Oncoprotein LMP1 to Exosomes

C-Terminal Farnesylation of UCH-L1 Plays a Role in Transport of Epstein-Barr Virus Primary Oncoprotein LMP1 to Exosomes

ABSTRACT Increasing evidence shows that exosomes are key regulators in cancer cell-to-cell communication. Several reports on Epstein-Barr virus (EBV)-related malignancies demonstrate that latent membrane protein 1 (LMP1) secreted by exosomes derived from EBV- or LMP1-positive cells can promote cance...

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Autores principales: E. Kobayashi, M. Aga, S. Kondo, C. Whitehurst, T. Yoshizaki, J. S. Pagano, J. Shackelford
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
exosome
farnesylation
metastasis
oncovirus
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/818a2f0f9c7a449eadcf05f9e5d19bae
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