Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells
Conventional T cell subsets are selected in the thymus by peptide bearing MHC expressed by cortical epithelial cells, in contrast cortical thymocytes express non-peptide bearing MHC molecules including CD1d and MR1 and select iNKT and MAIT cell populations respectively. Here, the authors generate a...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/81950d9bb43444afbba3babc90ee020b |
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