A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy
It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect.
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| Lenguaje: | EN |
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Nature Portfolio
2018
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| Acceso en línea: | https://doaj.org/article/8199cec7a8594322a3448b9ce1685a6b |
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oai:doaj.org-article:8199cec7a8594322a3448b9ce1685a6b2021-12-02T16:49:20ZA discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy10.1038/s41467-018-06574-72041-1723https://doaj.org/article/8199cec7a8594322a3448b9ce1685a6b2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06574-7https://doaj.org/toc/2041-1723It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect.Guocan YuShan YuManik Lal SahaJiong ZhouTimothy R. CookBryant C. YungJin ChenZhengwei MaoFuwu ZhangZijian ZhouYijing LiuLi ShaoSheng WangChangyou GaoFeihe HuangPeter J. StangXiaoyuan ChenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Guocan Yu Shan Yu Manik Lal Saha Jiong Zhou Timothy R. Cook Bryant C. Yung Jin Chen Zhengwei Mao Fuwu Zhang Zijian Zhou Yijing Liu Li Shao Sheng Wang Changyou Gao Feihe Huang Peter J. Stang Xiaoyuan Chen A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| description |
It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect. |
| format |
article |
| author |
Guocan Yu Shan Yu Manik Lal Saha Jiong Zhou Timothy R. Cook Bryant C. Yung Jin Chen Zhengwei Mao Fuwu Zhang Zijian Zhou Yijing Liu Li Shao Sheng Wang Changyou Gao Feihe Huang Peter J. Stang Xiaoyuan Chen |
| author_facet |
Guocan Yu Shan Yu Manik Lal Saha Jiong Zhou Timothy R. Cook Bryant C. Yung Jin Chen Zhengwei Mao Fuwu Zhang Zijian Zhou Yijing Liu Li Shao Sheng Wang Changyou Gao Feihe Huang Peter J. Stang Xiaoyuan Chen |
| author_sort |
Guocan Yu |
| title |
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| title_short |
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| title_full |
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| title_fullStr |
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| title_full_unstemmed |
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| title_sort |
discrete organoplatinum(ii) metallacage as a multimodality theranostic platform for cancer photochemotherapy |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/8199cec7a8594322a3448b9ce1685a6b |
| work_keys_str_mv |
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