Concurrent and orthogonal gold(I) and ruthenium(II) catalysis inside living cells

Transition-metal catalysis in living cells poses numerous challenges in terms of biocompatibility, and complex stability and reactivity. Here, the authors report a bioorthogonal gold-catalyzed C-C coupling reaction, occurring in living mammalian cells, even in parallel with a ruthenium-catalyzed dea...

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Autores principales: Cristian Vidal, María Tomás-Gamasa, Paolo Destito, Fernando López, José L. Mascareñas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/819f51fd824a4edb97a24c6e05c92ace
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Sumario:Transition-metal catalysis in living cells poses numerous challenges in terms of biocompatibility, and complex stability and reactivity. Here, the authors report a bioorthogonal gold-catalyzed C-C coupling reaction, occurring in living mammalian cells, even in parallel with a ruthenium-catalyzed deallylation reaction.