Targeting the CK1α/CBX4 axis for metastasis in osteosarcoma

Osteosarcoma is an aggressive tumour and little is known the mechanisms underpinning its highly metastatic nature. Here, the authors highlight a role for the CK1α/CBX4 axis in driving metastasis, suggesting that this pathway might be targeted for therapeutic benefit.

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Bibliographic Details
Main Authors: Xin Wang, Ge Qin, Xiaoting Liang, Wen Wang, Zhuo Wang, Dan Liao, Li Zhong, Ruhua Zhang, Yi-Xin Zeng, Yuanzhong Wu, Tiebang Kang
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/81b4b922e62c43c09d427d7c2872a2d6
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