Administration of E2 and NS1 siRNAs inhibit chikungunya virus replication in vitro and protects mice infected with the virus.

<h4>Background</h4>Chikungunya virus (CHIKV) has reemerged as a life threatening pathogen and caused large epidemics in several countries. So far, no licensed vaccine or effective antivirals are available and the treatment remains symptomatic. In this context, development of effective an...

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Autores principales: Deepti Parashar, Mandar S Paingankar, Satyendra Kumar, Mangesh D Gokhale, A B Sudeep, Sapana B Shinde, V A Arankalle
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/81bb83945c5745d9b113ea6fdfc03e64
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