Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant <italic toggle="yes">Pseudomonas aeruginosa</italic> Mutants Overexpressing Efflux Pumps
ABSTRACT It is generally assumed that the acquisition of antibiotic resistance is associated with a fitness cost. We have shown that overexpression of the MexEF-OprN efflux pump does not decrease the fitness of a resistant Pseudomonas aeruginosa strain compared to its wild-type counterpart. This lac...
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Autores principales: | Jorge Olivares Pacheco, Carolina Alvarez-Ortega, Manuel Alcalde Rico, José Luis Martínez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/81c0d553a1c8444da725d9b2574b3ab4 |
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