Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant <italic toggle="yes">Pseudomonas aeruginosa</italic> Mutants Overexpressing Efflux Pumps

ABSTRACT It is generally assumed that the acquisition of antibiotic resistance is associated with a fitness cost. We have shown that overexpression of the MexEF-OprN efflux pump does not decrease the fitness of a resistant Pseudomonas aeruginosa strain compared to its wild-type counterpart. This lac...

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Autores principales: Jorge Olivares Pacheco, Carolina Alvarez-Ortega, Manuel Alcalde Rico, José Luis Martínez
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/81c0d553a1c8444da725d9b2574b3ab4
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