Directed nickel-catalyzed regio- and diastereoselective arylamination of unactivated alkenes

Few methods exist to add a carbon and nitrogen atom across an unfunctionalized alkene. Here the authors show a method to regio- and diastereoselectively add aryl and amino groups to terminal and internal alkenes, via nickel catalysis and a removable directing group.

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Autores principales: Leipeng Xie, Shenghao Wang, Lanlan Zhang, Lei Zhao, Chun Luo, Linping Mu, Xiuguang Wang, Chao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/81d9ed20756849d89abf2dee50a2638c
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