Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses

Selective autophagy describes the selective degradation of cellular components upon stress or nutrient deficiency, but whether it modulates innate immunity is unclear. Here the authors show that Drosophila Kenny may be an evolution-selected autophagy receptor for the down-regulation of innate NF-κB...

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Autores principales:	Radu Tusco, Anne-Claire Jacomin, Ashish Jain, Bridget S. Penman, Kenneth Bowitz Larsen, Terje Johansen, Ioannis P. Nezis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/81ed953ad9ea48a8980dd1e3764b1e04
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spelling	oai:doaj.org-article:81ed953ad9ea48a8980dd1e3764b1e042021-12-02T14:42:37ZKenny mediates selective autophagic degradation of the IKK complex to control innate immune responses10.1038/s41467-017-01287-92041-1723https://doaj.org/article/81ed953ad9ea48a8980dd1e3764b1e042017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01287-9https://doaj.org/toc/2041-1723Selective autophagy describes the selective degradation of cellular components upon stress or nutrient deficiency, but whether it modulates innate immunity is unclear. Here the authors show that Drosophila Kenny may be an evolution-selected autophagy receptor for the down-regulation of innate NF-κB activationRadu TuscoAnne-Claire JacominAshish JainBridget S. PenmanKenneth Bowitz LarsenTerje JohansenIoannis P. NezisNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Radu Tusco Anne-Claire Jacomin Ashish Jain Bridget S. Penman Kenneth Bowitz Larsen Terje Johansen Ioannis P. Nezis Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
description	Selective autophagy describes the selective degradation of cellular components upon stress or nutrient deficiency, but whether it modulates innate immunity is unclear. Here the authors show that Drosophila Kenny may be an evolution-selected autophagy receptor for the down-regulation of innate NF-κB activation
format	article
author	Radu Tusco Anne-Claire Jacomin Ashish Jain Bridget S. Penman Kenneth Bowitz Larsen Terje Johansen Ioannis P. Nezis
author_facet	Radu Tusco Anne-Claire Jacomin Ashish Jain Bridget S. Penman Kenneth Bowitz Larsen Terje Johansen Ioannis P. Nezis
author_sort	Radu Tusco
title	Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
title_short	Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
title_full	Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
title_fullStr	Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
title_full_unstemmed	Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
title_sort	kenny mediates selective autophagic degradation of the ikk complex to control innate immune responses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/81ed953ad9ea48a8980dd1e3764b1e04
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Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses

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