Dysregulated miRNAs and their pathogenic implications for the neurometabolic disease propionic acidemia

Dysregulated miRNAs and their pathogenic implications for the neurometabolic disease propionic acidemia

Abstract miRNome expression profiling was performed in a mouse model of propionic acidemia (PA) and in patients’ plasma samples to investigate the role of miRNAs in the pathophysiology of the disease and to identify novel biomarkers and therapeutic targets. PA is a potentially lethal neurometabolic...

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Autores principales: Ana Rivera-Barahona, Alejandro Fulgencio-Covián, Celia Pérez-Cerdá, Ricardo Ramos, Michael A. Barry, Magdalena Ugarte, Belén Pérez, Eva Richard, Lourdes R Desviat
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/81f02db56c494ec3a74cb8d4bc20b7c9
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