Dynamics of high viscosity contrast confluent microfluidic flows

Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large vi...

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Autores principales:	Michael E. Kurdzinski, Berrak Gol, Aaron Co Hee, Peter Thurgood, Jiu Yang Zhu, Phred Petersen, Arnan Mitchell, Khashayar Khoshmanesh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/81f8c0f6d1034825bd243d5b9158e489
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spelling	oai:doaj.org-article:81f8c0f6d1034825bd243d5b9158e4892021-12-02T16:06:18ZDynamics of high viscosity contrast confluent microfluidic flows10.1038/s41598-017-06260-62045-2322https://doaj.org/article/81f8c0f6d1034825bd243d5b9158e4892017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06260-6https://doaj.org/toc/2045-2322Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large viscosity contrast between the neighbouring flows leading to unique instability patterns along their interface. Here, we study the dynamics of high viscosity contrast confluent flows – specifically a core flow made of highly viscous glycerol confined by sheath flows made of water within a microfluidic flow focusing system. Our experiments indicate the formation of tapered core structures along the middle of the channel. Increasing the sheath flow rate shortens the tapered core, and importantly induces local instability patterns along the interface of core-sheath flows. The dynamics of such tapered core structures is governed by the intensity of instability patterns and the length of the core, according to which the core structure can experience stable, disturbed, broken or oscillated regimes. We have studied the dynamics of tapered core structures under these regimes. In particular, we have analysed the amplitude and frequency of core displacements during the broken core and oscillating core regimes, which have not been investigated before.Michael E. KurdzinskiBerrak GolAaron Co HeePeter ThurgoodJiu Yang ZhuPhred PetersenArnan MitchellKhashayar KhoshmaneshNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Michael E. Kurdzinski Berrak Gol Aaron Co Hee Peter Thurgood Jiu Yang Zhu Phred Petersen Arnan Mitchell Khashayar Khoshmanesh Dynamics of high viscosity contrast confluent microfluidic flows
description	Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large viscosity contrast between the neighbouring flows leading to unique instability patterns along their interface. Here, we study the dynamics of high viscosity contrast confluent flows – specifically a core flow made of highly viscous glycerol confined by sheath flows made of water within a microfluidic flow focusing system. Our experiments indicate the formation of tapered core structures along the middle of the channel. Increasing the sheath flow rate shortens the tapered core, and importantly induces local instability patterns along the interface of core-sheath flows. The dynamics of such tapered core structures is governed by the intensity of instability patterns and the length of the core, according to which the core structure can experience stable, disturbed, broken or oscillated regimes. We have studied the dynamics of tapered core structures under these regimes. In particular, we have analysed the amplitude and frequency of core displacements during the broken core and oscillating core regimes, which have not been investigated before.
format	article
author	Michael E. Kurdzinski Berrak Gol Aaron Co Hee Peter Thurgood Jiu Yang Zhu Phred Petersen Arnan Mitchell Khashayar Khoshmanesh
author_facet	Michael E. Kurdzinski Berrak Gol Aaron Co Hee Peter Thurgood Jiu Yang Zhu Phred Petersen Arnan Mitchell Khashayar Khoshmanesh
author_sort	Michael E. Kurdzinski
title	Dynamics of high viscosity contrast confluent microfluidic flows
title_short	Dynamics of high viscosity contrast confluent microfluidic flows
title_full	Dynamics of high viscosity contrast confluent microfluidic flows
title_fullStr	Dynamics of high viscosity contrast confluent microfluidic flows
title_full_unstemmed	Dynamics of high viscosity contrast confluent microfluidic flows
title_sort	dynamics of high viscosity contrast confluent microfluidic flows
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/81f8c0f6d1034825bd243d5b9158e489
work_keys_str_mv	AT michaelekurdzinski dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT berrakgol dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT aaroncohee dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT peterthurgood dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT jiuyangzhu dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT phredpetersen dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT arnanmitchell dynamicsofhighviscositycontrastconfluentmicrofluidicflows AT khashayarkhoshmanesh dynamicsofhighviscositycontrastconfluentmicrofluidicflows
_version_	1718385035549081600

Dynamics of high viscosity contrast confluent microfluidic flows

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