Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants...

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Autores principales: Agnieszka Tudek, Paweł S. Krawczyk, Seweryn Mroczek, Rafał Tomecki, Matti Turtola, Katarzyna Matylla-Kulińska, Torben Heick Jensen, Andrzej Dziembowski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/81fd2f0b2b364117add539bf1a1b1ef9
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Sumario:RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants.