Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants...

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Autores principales: Agnieszka Tudek, Paweł S. Krawczyk, Seweryn Mroczek, Rafał Tomecki, Matti Turtola, Katarzyna Matylla-Kulińska, Torben Heick Jensen, Andrzej Dziembowski
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/81fd2f0b2b364117add539bf1a1b1ef9
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spelling oai:doaj.org-article:81fd2f0b2b364117add539bf1a1b1ef92021-12-02T16:45:42ZGlobal view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae10.1038/s41467-021-25251-w2041-1723https://doaj.org/article/81fd2f0b2b364117add539bf1a1b1ef92021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25251-whttps://doaj.org/toc/2041-1723RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants.Agnieszka TudekPaweł S. KrawczykSeweryn MroczekRafał TomeckiMatti TurtolaKatarzyna Matylla-KulińskaTorben Heick JensenAndrzej DziembowskiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Agnieszka Tudek
Paweł S. Krawczyk
Seweryn Mroczek
Rafał Tomecki
Matti Turtola
Katarzyna Matylla-Kulińska
Torben Heick Jensen
Andrzej Dziembowski
Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
description RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants.
format article
author Agnieszka Tudek
Paweł S. Krawczyk
Seweryn Mroczek
Rafał Tomecki
Matti Turtola
Katarzyna Matylla-Kulińska
Torben Heick Jensen
Andrzej Dziembowski
author_facet Agnieszka Tudek
Paweł S. Krawczyk
Seweryn Mroczek
Rafał Tomecki
Matti Turtola
Katarzyna Matylla-Kulińska
Torben Heick Jensen
Andrzej Dziembowski
author_sort Agnieszka Tudek
title Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
title_short Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
title_full Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
title_fullStr Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
title_full_unstemmed Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
title_sort global view on the metabolism of rna poly(a) tails in yeast saccharomyces cerevisiae
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/81fd2f0b2b364117add539bf1a1b1ef9
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