The role of Helicobacter pylori in complex human comorbidity

One of the main features of modern medicine is the fact that most somatic diseases lose their mononosological character, acquiring the status of comorbidity. Comorbidity has become a separate research area in various specialties of medicine and is currently being formalized into a system of knowledg...

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Autores principales: A. Sergeeva, V. Shkarin, O. Kovalishena
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Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2019
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Acceso en línea:https://doaj.org/article/81fd6e6dd94949519174b9cd49477b7d
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spelling oai:doaj.org-article:81fd6e6dd94949519174b9cd49477b7d2021-11-22T07:09:56ZThe role of Helicobacter pylori in complex human comorbidity2220-76192313-739810.15789/2220-7619-TRO-1667https://doaj.org/article/81fd6e6dd94949519174b9cd49477b7d2019-06-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/1667https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398One of the main features of modern medicine is the fact that most somatic diseases lose their mononosological character, acquiring the status of comorbidity. Comorbidity has become a separate research area in various specialties of medicine and is currently being formalized into a system of knowledge about the patterns of combination of diseases. With regard to infectious pathology, the term "comorbidity" is rarely mentioned. In the conventional sense, comorbidity is understood as a combination of two or more diseases in a patient at the same time.In our opinion, the term "comorbidity" can be applied from the standpoint of the simultaneous combination of somatic and infectious diseases, but with a certain addition. In particular, it can be used in relation to somatic pathology with simultaneous combination with both monoinfection and polyetiologic. This is "complex comorbidity", which should be understood as "a complex pathological condition of a person, characterized by a simultaneous or sequential combination of psychosomatic and infectious pathology. It can take place when one or more infectious diseases are combined in combination with psychosomatic nosologies consisting of one or more units. "Over the past decade, a significant number of works have appeared on the role of H. pylori in the etiology and pathogenesis of a large number of somatic diseases. H. pylori plays in the development of many diseases - both associated with the stomach and determining the damage to other organs and systems. The clinical significance of this infection is determined by its leading role in the formation of chronic gastritis, gastric ulcer and duodenal ulcer, MALT lymphoma, and gastric adenocarcinoma. There is good evidence for the association of H. pylori infection with idiopathic iron deficiency anemia and idiopathic thrombocytopenic purpura. The clinical aspects of H. pylori infection are heterogeneous and include a wide range of pathologies, the evidence base for which at both the pathogenetic and clinical levels continues to expand.A. SergeevaV. ShkarinO. KovalishenaSankt-Peterburg : NIIÈM imeni Pasteraarticlecomorbidity, helicobacter pylori, systemic lupus erythematosus, progressive systemic sclerosis, rheumatoid arthritis, raynaud's syndromeInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 0, Iss 0 (2019)
institution DOAJ
collection DOAJ
language RU
topic comorbidity, helicobacter pylori, systemic lupus erythematosus, progressive systemic sclerosis, rheumatoid arthritis, raynaud's syndrome
Infectious and parasitic diseases
RC109-216
spellingShingle comorbidity, helicobacter pylori, systemic lupus erythematosus, progressive systemic sclerosis, rheumatoid arthritis, raynaud's syndrome
Infectious and parasitic diseases
RC109-216
A. Sergeeva
V. Shkarin
O. Kovalishena
The role of Helicobacter pylori in complex human comorbidity
description One of the main features of modern medicine is the fact that most somatic diseases lose their mononosological character, acquiring the status of comorbidity. Comorbidity has become a separate research area in various specialties of medicine and is currently being formalized into a system of knowledge about the patterns of combination of diseases. With regard to infectious pathology, the term "comorbidity" is rarely mentioned. In the conventional sense, comorbidity is understood as a combination of two or more diseases in a patient at the same time.In our opinion, the term "comorbidity" can be applied from the standpoint of the simultaneous combination of somatic and infectious diseases, but with a certain addition. In particular, it can be used in relation to somatic pathology with simultaneous combination with both monoinfection and polyetiologic. This is "complex comorbidity", which should be understood as "a complex pathological condition of a person, characterized by a simultaneous or sequential combination of psychosomatic and infectious pathology. It can take place when one or more infectious diseases are combined in combination with psychosomatic nosologies consisting of one or more units. "Over the past decade, a significant number of works have appeared on the role of H. pylori in the etiology and pathogenesis of a large number of somatic diseases. H. pylori plays in the development of many diseases - both associated with the stomach and determining the damage to other organs and systems. The clinical significance of this infection is determined by its leading role in the formation of chronic gastritis, gastric ulcer and duodenal ulcer, MALT lymphoma, and gastric adenocarcinoma. There is good evidence for the association of H. pylori infection with idiopathic iron deficiency anemia and idiopathic thrombocytopenic purpura. The clinical aspects of H. pylori infection are heterogeneous and include a wide range of pathologies, the evidence base for which at both the pathogenetic and clinical levels continues to expand.
format article
author A. Sergeeva
V. Shkarin
O. Kovalishena
author_facet A. Sergeeva
V. Shkarin
O. Kovalishena
author_sort A. Sergeeva
title The role of Helicobacter pylori in complex human comorbidity
title_short The role of Helicobacter pylori in complex human comorbidity
title_full The role of Helicobacter pylori in complex human comorbidity
title_fullStr The role of Helicobacter pylori in complex human comorbidity
title_full_unstemmed The role of Helicobacter pylori in complex human comorbidity
title_sort role of helicobacter pylori in complex human comorbidity
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2019
url https://doaj.org/article/81fd6e6dd94949519174b9cd49477b7d
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AT asergeeva roleofhelicobacterpyloriincomplexhumancomorbidity
AT vshkarin roleofhelicobacterpyloriincomplexhumancomorbidity
AT okovalishena roleofhelicobacterpyloriincomplexhumancomorbidity
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