Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil

Objective: To assess the microbiological profile of culture results of patients admitted in a public university hospital from Fortaleza, Brazil. Methods: This is a descriptive and prospective study with patients being followed up in an antimicrobial stewardship program and in use of reserve or stra...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Thalita M. FREIRE, Elana F. CHAVES, José M. ALCÂNTARA-NETO, Paulo P. SOUSA, Jorge N. RODRIGUES, Henry C. REIS
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/82113707fbcd457ea2c7b6c9849a9897
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:82113707fbcd457ea2c7b6c9849a9897
record_format	dspace
spelling	oai:doaj.org-article:82113707fbcd457ea2c7b6c9849a98972021-11-28T02:45:01ZMicrobiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil10.30968/rbfhss.2020.112.03712179-59242316-7750https://doaj.org/article/82113707fbcd457ea2c7b6c9849a98972020-07-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/371https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objective: To assess the microbiological profile of culture results of patients admitted in a public university hospital from Fortaleza, Brazil. Methods: This is a descriptive and prospective study with patients being followed up in an antimicrobial stewardship program and in use of reserve or strategic antimicrobial agents, which had cultures requested between May and November 2017. Data was obtained from the patient’s records, registered and analyzed using Excel spreadsheets and Graph Pad Prism statistical software. Results: Male patients (60.2%), non-elderly (63.6%), with hospital discharge clinical outcome (84.7%) and kidney transplant specialty (35.6%) prevailed. We analyzed the result of 490 cultures, with a higher frequency of urine cultures (35.3%) and blood cultures (34.7%) than others cultures. The specialty with most requests was kidney and liver transplant. 19.8% of the cultures were positive, predominantly gram-negative bacilli (72.2%), especially in the urine cultures of transplant patients. Microbiological analysis showed that Klebsiella pneumoniae (49.1%) and Escherichia coli (39.6%) were the bacteria most frequently found. Regarding the microbial resistance profile, we identified carbapenemase producing bacteria (16.7%), Extended spectrum beta-lactamases (ESBL; 33.3%) within the group of gramnegative bacilli and Vancomycin-resistence enterococcus (VRE; 13.5%) within the group of gram-positive cocci. Conclusions: The study enabled the knowledge of the profile of microorganisms isolated in the wards under study, which is of fundamental importance for local epidemiological studies and for the control of microbial resistance. Thalita M. FREIREElana F. CHAVESJosé M. ALCÂNTARA-NETOPaulo P. SOUSAJorge N. RODRIGUESHenry C. REISSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 11, Iss 2 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Thalita M. FREIRE Elana F. CHAVES José M. ALCÂNTARA-NETO Paulo P. SOUSA Jorge N. RODRIGUES Henry C. REIS Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
description	Objective: To assess the microbiological profile of culture results of patients admitted in a public university hospital from Fortaleza, Brazil. Methods: This is a descriptive and prospective study with patients being followed up in an antimicrobial stewardship program and in use of reserve or strategic antimicrobial agents, which had cultures requested between May and November 2017. Data was obtained from the patient’s records, registered and analyzed using Excel spreadsheets and Graph Pad Prism statistical software. Results: Male patients (60.2%), non-elderly (63.6%), with hospital discharge clinical outcome (84.7%) and kidney transplant specialty (35.6%) prevailed. We analyzed the result of 490 cultures, with a higher frequency of urine cultures (35.3%) and blood cultures (34.7%) than others cultures. The specialty with most requests was kidney and liver transplant. 19.8% of the cultures were positive, predominantly gram-negative bacilli (72.2%), especially in the urine cultures of transplant patients. Microbiological analysis showed that Klebsiella pneumoniae (49.1%) and Escherichia coli (39.6%) were the bacteria most frequently found. Regarding the microbial resistance profile, we identified carbapenemase producing bacteria (16.7%), Extended spectrum beta-lactamases (ESBL; 33.3%) within the group of gramnegative bacilli and Vancomycin-resistence enterococcus (VRE; 13.5%) within the group of gram-positive cocci. Conclusions: The study enabled the knowledge of the profile of microorganisms isolated in the wards under study, which is of fundamental importance for local epidemiological studies and for the control of microbial resistance.
format	article
author	Thalita M. FREIRE Elana F. CHAVES José M. ALCÂNTARA-NETO Paulo P. SOUSA Jorge N. RODRIGUES Henry C. REIS
author_facet	Thalita M. FREIRE Elana F. CHAVES José M. ALCÂNTARA-NETO Paulo P. SOUSA Jorge N. RODRIGUES Henry C. REIS
author_sort	Thalita M. FREIRE
title	Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
title_short	Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
title_full	Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
title_fullStr	Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
title_full_unstemmed	Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil
title_sort	microbiological profile of isolated specimens in patients admitted to a university hospital from fortaleza, brazil
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/82113707fbcd457ea2c7b6c9849a9897
work_keys_str_mv	AT thalitamfreire microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil AT elanafchaves microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil AT josemalcantaraneto microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil AT paulopsousa microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil AT jorgenrodrigues microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil AT henrycreis microbiologicalprofileofisolatedspecimensinpatientsadmittedtoauniversityhospitalfromfortalezabrazil
_version_	1718408449685979136

Microbiological profile of isolated specimens in patients admitted to a university hospital from Fortaleza, Brazil

Ejemplares similares