CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ,...
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2014
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oai:doaj.org-article:821b374d422a4da783a8805779aba27b2021-11-18T08:03:37ZCYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER1563-06252313-741X10.15789/1563-0625-2009-1-29-34https://doaj.org/article/821b374d422a4da783a8805779aba27b2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/42https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade.A. I. AutenshlussA. V. SosninaE. S. MikhailovaD. V. MorozovN. A. VaraksinM. Yu. RukavishnikovYu. N. KozlovaA. V. Kan’shinaSPb RAACIarticlecytokinesantibodieshistopatologic patternmalignant neoplasmgastorintestinal cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 29-34 (2014) |
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RU |
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cytokines antibodies histopatologic pattern malignant neoplasm gastorintestinal cancer Immunologic diseases. Allergy RC581-607 |
spellingShingle |
cytokines antibodies histopatologic pattern malignant neoplasm gastorintestinal cancer Immunologic diseases. Allergy RC581-607 A. I. Autenshluss A. V. Sosnina E. S. Mikhailova D. V. Morozov N. A. Varaksin M. Yu. Rukavishnikov Yu. N. Kozlova A. V. Kan’shina CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
description |
The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade. |
format |
article |
author |
A. I. Autenshluss A. V. Sosnina E. S. Mikhailova D. V. Morozov N. A. Varaksin M. Yu. Rukavishnikov Yu. N. Kozlova A. V. Kan’shina |
author_facet |
A. I. Autenshluss A. V. Sosnina E. S. Mikhailova D. V. Morozov N. A. Varaksin M. Yu. Rukavishnikov Yu. N. Kozlova A. V. Kan’shina |
author_sort |
A. I. Autenshluss |
title |
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
title_short |
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
title_full |
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
title_fullStr |
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
title_full_unstemmed |
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER |
title_sort |
cytokines and histopathologic pattern of malignant neoplasms in gastrointestinal cancer |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/821b374d422a4da783a8805779aba27b |
work_keys_str_mv |
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