CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER

The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ,...

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Autores principales: A. I. Autenshluss, A. V. Sosnina, E. S. Mikhailova, D. V. Morozov, N. A. Varaksin, M. Yu. Rukavishnikov, Yu. N. Kozlova, A. V. Kan’shina
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Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:821b374d422a4da783a8805779aba27b2021-11-18T08:03:37ZCYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER1563-06252313-741X10.15789/1563-0625-2009-1-29-34https://doaj.org/article/821b374d422a4da783a8805779aba27b2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/42https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade.A. I. AutenshlussA. V. SosninaE. S. MikhailovaD. V. MorozovN. A. VaraksinM. Yu. RukavishnikovYu. N. KozlovaA. V. Kan’shinaSPb RAACIarticlecytokinesantibodieshistopatologic patternmalignant neoplasmgastorintestinal cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 29-34 (2014)
institution DOAJ
collection DOAJ
language RU
topic cytokines
antibodies
histopatologic pattern
malignant neoplasm
gastorintestinal cancer
Immunologic diseases. Allergy
RC581-607
spellingShingle cytokines
antibodies
histopatologic pattern
malignant neoplasm
gastorintestinal cancer
Immunologic diseases. Allergy
RC581-607
A. I. Autenshluss
A. V. Sosnina
E. S. Mikhailova
D. V. Morozov
N. A. Varaksin
M. Yu. Rukavishnikov
Yu. N. Kozlova
A. V. Kan’shina
CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
description The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade.
format article
author A. I. Autenshluss
A. V. Sosnina
E. S. Mikhailova
D. V. Morozov
N. A. Varaksin
M. Yu. Rukavishnikov
Yu. N. Kozlova
A. V. Kan’shina
author_facet A. I. Autenshluss
A. V. Sosnina
E. S. Mikhailova
D. V. Morozov
N. A. Varaksin
M. Yu. Rukavishnikov
Yu. N. Kozlova
A. V. Kan’shina
author_sort A. I. Autenshluss
title CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
title_short CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
title_full CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
title_fullStr CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
title_full_unstemmed CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
title_sort cytokines and histopathologic pattern of malignant neoplasms in gastrointestinal cancer
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/821b374d422a4da783a8805779aba27b
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