Prevalence of anti HDV in HBV carriers in Babol during 2000-02
Background and Objective: Hepatitis D virus is a defective RNA containing virus that only infects human in the presence of HBV either as a coinfection or as superinfection in HBV carriers. Hepatitis D may accelerate the progress of chronic HBV infection to chronic hepatitis, cirrhosis and hepatocell...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN FA |
| Publicado: |
Babol University of Medical Sciences
2004
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/8223df7b227342fc947abf7a359326a1 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Background and Objective: Hepatitis D virus is a defective RNA containing virus that only infects human in the presence of HBV either as a coinfection or as superinfection in HBV carriers. Hepatitis D may accelerate the progress of chronic HBV infection to chronic hepatitis, cirrhosis and hepatocellular carcinoma. More than 3% of population in our country is chronic HBV carriers. The aim of this study was to determine the prevalence of anti HDV in asymptomatic HBV carriers in Babol. Methods: This prospective study was performed on all HBV carriers who were diagnosed by Babol blood bank center and also their infected family members during 2000-2002. In all cases, anti HDV were assayed by Elisa. Proportions were compared by T-test, Chi-square and Fisher’s exact tests. Findings: From 546 cases of HBV carriers, 319 (58.4%) were male and 227 (41.6%) were female. 489 (89.6%) cases of anti HBe+ (Mean age±SD 32.13±11.9 years) and 57 (10.4%) cases of HbeAg+ (Mean age±SD 23.7±11.24 years) were studied. Anti HDV was positive in 6 (1.9%) of males and 5 (2.2%) of females (P=0.769). Anti HDV was positive in 7 (1.4%) cases of Anti HBe+ and 4 (7%) of HbeAg+ cases (P=0.02). in total, the prevalence of anti HDV was 2% in all patients. Conclusion: The results showed that HDV is endemic in our area and its prevalence is higher in HbeAg+ cases. The study of prevalence of anti HDV in high-risk groups is recommended. |
|---|