Prevalence of anti HDV in HBV carriers in Babol during 2000-02

Background and Objective: Hepatitis D virus is a defective RNA containing virus that only infects human in the presence of HBV either as a coinfection or as superinfection in HBV carriers. Hepatitis D may accelerate the progress of chronic HBV infection to chronic hepatitis, cirrhosis and hepatocell...

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Autores principales:	MR Hassanjani Roshan, AA Baiki, MJ Soleimani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2004
Materias:	hbv carriers hepatitis d anti hdv prevalence Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8223df7b227342fc947abf7a359326a1
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spelling	oai:doaj.org-article:8223df7b227342fc947abf7a359326a12021-11-10T09:15:56ZPrevalence of anti HDV in HBV carriers in Babol during 2000-021561-41072251-7170https://doaj.org/article/8223df7b227342fc947abf7a359326a12004-01-01T00:00:00Zhttp://jbums.org/article-1-2739-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Hepatitis D virus is a defective RNA containing virus that only infects human in the presence of HBV either as a coinfection or as superinfection in HBV carriers. Hepatitis D may accelerate the progress of chronic HBV infection to chronic hepatitis, cirrhosis and hepatocellular carcinoma. More than 3% of population in our country is chronic HBV carriers. The aim of this study was to determine the prevalence of anti HDV in asymptomatic HBV carriers in Babol. Methods: This prospective study was performed on all HBV carriers who were diagnosed by Babol blood bank center and also their infected family members during 2000-2002. In all cases, anti HDV were assayed by Elisa. Proportions were compared by T-test, Chi-square and Fisher’s exact tests. Findings: From 546 cases of HBV carriers, 319 (58.4%) were male and 227 (41.6%) were female. 489 (89.6%) cases of anti HBe+ (Mean age±SD 32.13±11.9 years) and 57 (10.4%) cases of HbeAg+ (Mean age±SD 23.7±11.24 years) were studied. Anti HDV was positive in 6 (1.9%) of males and 5 (2.2%) of females (P=0.769). Anti HDV was positive in 7 (1.4%) cases of Anti HBe+ and 4 (7%) of HbeAg+ cases (P=0.02). in total, the prevalence of anti HDV was 2% in all patients. Conclusion: The results showed that HDV is endemic in our area and its prevalence is higher in HbeAg+ cases. The study of prevalence of anti HDV in high-risk groups is recommended.MR Hassanjani RoshanAA BaikiMJ SoleimaniBabol University of Medical Sciencesarticlehbv carriershepatitis danti hdvprevalenceMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 6, Iss 1, Pp 50-54 (2004)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	hbv carriers hepatitis d anti hdv prevalence Medicine R Medicine (General) R5-920
spellingShingle	hbv carriers hepatitis d anti hdv prevalence Medicine R Medicine (General) R5-920 MR Hassanjani Roshan AA Baiki MJ Soleimani Prevalence of anti HDV in HBV carriers in Babol during 2000-02
description	Background and Objective: Hepatitis D virus is a defective RNA containing virus that only infects human in the presence of HBV either as a coinfection or as superinfection in HBV carriers. Hepatitis D may accelerate the progress of chronic HBV infection to chronic hepatitis, cirrhosis and hepatocellular carcinoma. More than 3% of population in our country is chronic HBV carriers. The aim of this study was to determine the prevalence of anti HDV in asymptomatic HBV carriers in Babol. Methods: This prospective study was performed on all HBV carriers who were diagnosed by Babol blood bank center and also their infected family members during 2000-2002. In all cases, anti HDV were assayed by Elisa. Proportions were compared by T-test, Chi-square and Fisher’s exact tests. Findings: From 546 cases of HBV carriers, 319 (58.4%) were male and 227 (41.6%) were female. 489 (89.6%) cases of anti HBe+ (Mean age±SD 32.13±11.9 years) and 57 (10.4%) cases of HbeAg+ (Mean age±SD 23.7±11.24 years) were studied. Anti HDV was positive in 6 (1.9%) of males and 5 (2.2%) of females (P=0.769). Anti HDV was positive in 7 (1.4%) cases of Anti HBe+ and 4 (7%) of HbeAg+ cases (P=0.02). in total, the prevalence of anti HDV was 2% in all patients. Conclusion: The results showed that HDV is endemic in our area and its prevalence is higher in HbeAg+ cases. The study of prevalence of anti HDV in high-risk groups is recommended.
format	article
author	MR Hassanjani Roshan AA Baiki MJ Soleimani
author_facet	MR Hassanjani Roshan AA Baiki MJ Soleimani
author_sort	MR Hassanjani Roshan
title	Prevalence of anti HDV in HBV carriers in Babol during 2000-02
title_short	Prevalence of anti HDV in HBV carriers in Babol during 2000-02
title_full	Prevalence of anti HDV in HBV carriers in Babol during 2000-02
title_fullStr	Prevalence of anti HDV in HBV carriers in Babol during 2000-02
title_full_unstemmed	Prevalence of anti HDV in HBV carriers in Babol during 2000-02
title_sort	prevalence of anti hdv in hbv carriers in babol during 2000-02
publisher	Babol University of Medical Sciences
publishDate	2004
url	https://doaj.org/article/8223df7b227342fc947abf7a359326a1
work_keys_str_mv	AT mrhassanjaniroshan prevalenceofantihdvinhbvcarriersinbabolduring200002 AT aabaiki prevalenceofantihdvinhbvcarriersinbabolduring200002 AT mjsoleimani prevalenceofantihdvinhbvcarriersinbabolduring200002
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Prevalence of anti HDV in HBV carriers in Babol during 2000-02

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