Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation
Hox genes regulate anterior–posterior axis formation but their role in cnidarians is unclear. Here, the authors disrupt Hox genes NvAx1 and NvAx6 in the starlet sea anemone, Nematostella vectensis, showing antagonist function in patterning the oral–aboral axis and a link to Wnt signaling.
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Nature Portfolio
2018
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oai:doaj.org-article:822e9a3de54442eeb8f16a20846fe8092021-12-02T13:23:48ZHox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation10.1038/s41467-018-04184-x2041-1723https://doaj.org/article/822e9a3de54442eeb8f16a20846fe8092018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04184-xhttps://doaj.org/toc/2041-1723Hox genes regulate anterior–posterior axis formation but their role in cnidarians is unclear. Here, the authors disrupt Hox genes NvAx1 and NvAx6 in the starlet sea anemone, Nematostella vectensis, showing antagonist function in patterning the oral–aboral axis and a link to Wnt signaling.Timothy Q. DuBucThomas B. StephensonAmber Q. RockMark Q. MartindaleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Timothy Q. DuBuc Thomas B. Stephenson Amber Q. Rock Mark Q. Martindale Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
description |
Hox genes regulate anterior–posterior axis formation but their role in cnidarians is unclear. Here, the authors disrupt Hox genes NvAx1 and NvAx6 in the starlet sea anemone, Nematostella vectensis, showing antagonist function in patterning the oral–aboral axis and a link to Wnt signaling. |
format |
article |
author |
Timothy Q. DuBuc Thomas B. Stephenson Amber Q. Rock Mark Q. Martindale |
author_facet |
Timothy Q. DuBuc Thomas B. Stephenson Amber Q. Rock Mark Q. Martindale |
author_sort |
Timothy Q. DuBuc |
title |
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
title_short |
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
title_full |
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
title_fullStr |
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
title_full_unstemmed |
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
title_sort |
hox and wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/822e9a3de54442eeb8f16a20846fe809 |
work_keys_str_mv |
AT timothyqdubuc hoxandwntpatterntheprimarybodyaxisofananthozoancnidarianbeforegastrulation AT thomasbstephenson hoxandwntpatterntheprimarybodyaxisofananthozoancnidarianbeforegastrulation AT amberqrock hoxandwntpatterntheprimarybodyaxisofananthozoancnidarianbeforegastrulation AT markqmartindale hoxandwntpatterntheprimarybodyaxisofananthozoancnidarianbeforegastrulation |
_version_ |
1718393162744987648 |