Anemia associated with chronic heart failure: current concepts

Ravish Shah, Anil K AgarwalDivision of Nephrology, The Ohio State University, Columbus, Ohio, USAAbstract: Anemia is a frequent comorbidity of heart failure and is associated with poor outcomes. Anemia in heart failure is considered to develop due to a complex interaction of iron deficiency, kidney...

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Autores principales:	Shah R, Agarwal AK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Anemia heart failure chronic kidney disease iron deficiency erythropoiesis stimulating agents intravenous iron Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/8246a3b3aedb45f0bca34008f33dd6bb
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id	oai:doaj.org-article:8246a3b3aedb45f0bca34008f33dd6bb
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spelling	oai:doaj.org-article:8246a3b3aedb45f0bca34008f33dd6bb2021-12-02T08:59:55ZAnemia associated with chronic heart failure: current concepts1178-1998https://doaj.org/article/8246a3b3aedb45f0bca34008f33dd6bb2013-02-01T00:00:00Zhttps://www.dovepress.com/anemia-associated-with-chronic-heart-failure-current-concepts-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Ravish Shah, Anil K AgarwalDivision of Nephrology, The Ohio State University, Columbus, Ohio, USAAbstract: Anemia is a frequent comorbidity of heart failure and is associated with poor outcomes. Anemia in heart failure is considered to develop due to a complex interaction of iron deficiency, kidney disease, and cytokine production, although micronutrient insufficiency and blood loss may contribute. Currently, treatment of anemia of heart failure lacks clear targets and specific therapy is not defined. Intravenous iron use has been shown to benefit anemic as well as nonanemic patients with heart failure. Treatment with erythropoietin-stimulating agents has been considered alone or in combination with iron, but robust evidence to dictate clear guidelines is not currently available. Available and emerging new agents in the treatment of anemia of heart failure will need to be tested in randomized, controlled studies.Keywords: anemia, heart failure, chronic kidney disease, elderly populationShah RAgarwal AKDove Medical PressarticleAnemiaheart failurechronic kidney diseaseiron deficiencyerythropoiesis stimulating agentsintravenous ironGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 8, Pp 111-122 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Anemia heart failure chronic kidney disease iron deficiency erythropoiesis stimulating agents intravenous iron Geriatrics RC952-954.6
spellingShingle	Anemia heart failure chronic kidney disease iron deficiency erythropoiesis stimulating agents intravenous iron Geriatrics RC952-954.6 Shah R Agarwal AK Anemia associated with chronic heart failure: current concepts
description	Ravish Shah, Anil K AgarwalDivision of Nephrology, The Ohio State University, Columbus, Ohio, USAAbstract: Anemia is a frequent comorbidity of heart failure and is associated with poor outcomes. Anemia in heart failure is considered to develop due to a complex interaction of iron deficiency, kidney disease, and cytokine production, although micronutrient insufficiency and blood loss may contribute. Currently, treatment of anemia of heart failure lacks clear targets and specific therapy is not defined. Intravenous iron use has been shown to benefit anemic as well as nonanemic patients with heart failure. Treatment with erythropoietin-stimulating agents has been considered alone or in combination with iron, but robust evidence to dictate clear guidelines is not currently available. Available and emerging new agents in the treatment of anemia of heart failure will need to be tested in randomized, controlled studies.Keywords: anemia, heart failure, chronic kidney disease, elderly population
format	article
author	Shah R Agarwal AK
author_facet	Shah R Agarwal AK
author_sort	Shah R
title	Anemia associated with chronic heart failure: current concepts
title_short	Anemia associated with chronic heart failure: current concepts
title_full	Anemia associated with chronic heart failure: current concepts
title_fullStr	Anemia associated with chronic heart failure: current concepts
title_full_unstemmed	Anemia associated with chronic heart failure: current concepts
title_sort	anemia associated with chronic heart failure: current concepts
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/8246a3b3aedb45f0bca34008f33dd6bb
work_keys_str_mv	AT shahr anemiaassociatedwithchronicheartfailurecurrentconcepts AT agarwalak anemiaassociatedwithchronicheartfailurecurrentconcepts
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Anemia associated with chronic heart failure: current concepts

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