Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice

Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal cord injury.

Guardado en:

Detalles Bibliográficos
Autores principales:	Qi Han, Josue D. Ordaz, Nai-Kui Liu, Zoe Richardson, Wei Wu, Yongzhi Xia, Wenrui Qu, Ying Wang, Heqiao Dai, Yi Ping Zhang, Christopher B. Shields, George M. Smith, Xiao-Ming Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/82507d8a067d4b81923c7112757684bb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:82507d8a067d4b81923c7112757684bb
record_format	dspace
spelling	oai:doaj.org-article:82507d8a067d4b81923c7112757684bb2021-12-02T17:33:10ZDescending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice10.1038/s41467-019-13854-32041-1723https://doaj.org/article/82507d8a067d4b81923c7112757684bb2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13854-3https://doaj.org/toc/2041-1723Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal cord injury.Qi HanJosue D. OrdazNai-Kui LiuZoe RichardsonWei WuYongzhi XiaWenrui QuYing WangHeqiao DaiYi Ping ZhangChristopher B. ShieldsGeorge M. SmithXiao-Ming XuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qi Han Josue D. Ordaz Nai-Kui Liu Zoe Richardson Wei Wu Yongzhi Xia Wenrui Qu Ying Wang Heqiao Dai Yi Ping Zhang Christopher B. Shields George M. Smith Xiao-Ming Xu Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
description	Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal cord injury.
format	article
author	Qi Han Josue D. Ordaz Nai-Kui Liu Zoe Richardson Wei Wu Yongzhi Xia Wenrui Qu Ying Wang Heqiao Dai Yi Ping Zhang Christopher B. Shields George M. Smith Xiao-Ming Xu
author_facet	Qi Han Josue D. Ordaz Nai-Kui Liu Zoe Richardson Wei Wu Yongzhi Xia Wenrui Qu Ying Wang Heqiao Dai Yi Ping Zhang Christopher B. Shields George M. Smith Xiao-Ming Xu
author_sort	Qi Han
title	Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
title_short	Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
title_full	Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
title_fullStr	Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
title_full_unstemmed	Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
title_sort	descending motor circuitry required for nt-3 mediated locomotor recovery after spinal cord injury in mice
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/82507d8a067d4b81923c7112757684bb
work_keys_str_mv	AT qihan descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT josuedordaz descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT naikuiliu descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT zoerichardson descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT weiwu descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT yongzhixia descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT wenruiqu descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT yingwang descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT heqiaodai descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT yipingzhang descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT christopherbshields descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT georgemsmith descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice AT xiaomingxu descendingmotorcircuitryrequiredfornt3mediatedlocomotorrecoveryafterspinalcordinjuryinmice
_version_	1718380071223296000

Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice

Ejemplares similares