DNA origami-based shape IDs for single-molecule nanomechanical genotyping

Atomic force microscopy allows for the imaging of molecules at a nanometre resolution. Here the authors combine AFM with self-assembling DNA origami structures to detect single-nucleotide polymorphisms and determine haplotypes.

Guardado en:
Detalles Bibliográficos
Autores principales: Honglu Zhang, Jie Chao, Dun Pan, Huajie Liu, Yu Qiang, Ke Liu, Chengjun Cui, Jianhua Chen, Qing Huang, Jun Hu, Lianhui Wang, Wei Huang, Yongyong Shi, Chunhai Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/82525457af4047a092cdbe2c023a2b5f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:82525457af4047a092cdbe2c023a2b5f
record_format dspace
spelling oai:doaj.org-article:82525457af4047a092cdbe2c023a2b5f2021-12-02T17:06:07ZDNA origami-based shape IDs for single-molecule nanomechanical genotyping10.1038/ncomms147382041-1723https://doaj.org/article/82525457af4047a092cdbe2c023a2b5f2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14738https://doaj.org/toc/2041-1723Atomic force microscopy allows for the imaging of molecules at a nanometre resolution. Here the authors combine AFM with self-assembling DNA origami structures to detect single-nucleotide polymorphisms and determine haplotypes.Honglu ZhangJie ChaoDun PanHuajie LiuYu QiangKe LiuChengjun CuiJianhua ChenQing HuangJun HuLianhui WangWei HuangYongyong ShiChunhai FanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Honglu Zhang
Jie Chao
Dun Pan
Huajie Liu
Yu Qiang
Ke Liu
Chengjun Cui
Jianhua Chen
Qing Huang
Jun Hu
Lianhui Wang
Wei Huang
Yongyong Shi
Chunhai Fan
DNA origami-based shape IDs for single-molecule nanomechanical genotyping
description Atomic force microscopy allows for the imaging of molecules at a nanometre resolution. Here the authors combine AFM with self-assembling DNA origami structures to detect single-nucleotide polymorphisms and determine haplotypes.
format article
author Honglu Zhang
Jie Chao
Dun Pan
Huajie Liu
Yu Qiang
Ke Liu
Chengjun Cui
Jianhua Chen
Qing Huang
Jun Hu
Lianhui Wang
Wei Huang
Yongyong Shi
Chunhai Fan
author_facet Honglu Zhang
Jie Chao
Dun Pan
Huajie Liu
Yu Qiang
Ke Liu
Chengjun Cui
Jianhua Chen
Qing Huang
Jun Hu
Lianhui Wang
Wei Huang
Yongyong Shi
Chunhai Fan
author_sort Honglu Zhang
title DNA origami-based shape IDs for single-molecule nanomechanical genotyping
title_short DNA origami-based shape IDs for single-molecule nanomechanical genotyping
title_full DNA origami-based shape IDs for single-molecule nanomechanical genotyping
title_fullStr DNA origami-based shape IDs for single-molecule nanomechanical genotyping
title_full_unstemmed DNA origami-based shape IDs for single-molecule nanomechanical genotyping
title_sort dna origami-based shape ids for single-molecule nanomechanical genotyping
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/82525457af4047a092cdbe2c023a2b5f
work_keys_str_mv AT hongluzhang dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT jiechao dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT dunpan dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT huajieliu dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT yuqiang dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT keliu dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT chengjuncui dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT jianhuachen dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT qinghuang dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT junhu dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT lianhuiwang dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT weihuang dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT yongyongshi dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
AT chunhaifan dnaorigamibasedshapeidsforsinglemoleculenanomechanicalgenotyping
_version_ 1718381739368251392