DNA origami-based shape IDs for single-molecule nanomechanical genotyping
Atomic force microscopy allows for the imaging of molecules at a nanometre resolution. Here the authors combine AFM with self-assembling DNA origami structures to detect single-nucleotide polymorphisms and determine haplotypes.
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Autores principales: | Honglu Zhang, Jie Chao, Dun Pan, Huajie Liu, Yu Qiang, Ke Liu, Chengjun Cui, Jianhua Chen, Qing Huang, Jun Hu, Lianhui Wang, Wei Huang, Yongyong Shi, Chunhai Fan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/82525457af4047a092cdbe2c023a2b5f |
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