Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry
Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patt...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2021
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| Accès en ligne: | https://doaj.org/article/8253fbb5f0b24bfb8e4abc3ad6bd08f4 |
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| Résumé: | Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patterns without derivatisation and standards. |
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