Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry
Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patt...
Guardado en:
Autores principales: | , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8253fbb5f0b24bfb8e4abc3ad6bd08f4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:8253fbb5f0b24bfb8e4abc3ad6bd08f4 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:8253fbb5f0b24bfb8e4abc3ad6bd08f42021-12-02T16:04:20ZStructural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry10.1038/s42004-021-00532-z2399-3669https://doaj.org/article/8253fbb5f0b24bfb8e4abc3ad6bd08f42021-06-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00532-zhttps://doaj.org/toc/2399-3669Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patterns without derivatisation and standards.Chia Yen LiewChu-Chun YenJien-Lian ChenShang-Ting TsaiSujeet PawarChung-Yi WuChi-Kung NiNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Chemistry QD1-999 |
spellingShingle |
Chemistry QD1-999 Chia Yen Liew Chu-Chun Yen Jien-Lian Chen Shang-Ting Tsai Sujeet Pawar Chung-Yi Wu Chi-Kung Ni Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
description |
Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patterns without derivatisation and standards. |
format |
article |
author |
Chia Yen Liew Chu-Chun Yen Jien-Lian Chen Shang-Ting Tsai Sujeet Pawar Chung-Yi Wu Chi-Kung Ni |
author_facet |
Chia Yen Liew Chu-Chun Yen Jien-Lian Chen Shang-Ting Tsai Sujeet Pawar Chung-Yi Wu Chi-Kung Ni |
author_sort |
Chia Yen Liew |
title |
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
title_short |
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
title_full |
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
title_fullStr |
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
title_full_unstemmed |
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry |
title_sort |
structural identification of n-glycan isomers using logically derived sequence tandem mass spectrometry |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/8253fbb5f0b24bfb8e4abc3ad6bd08f4 |
work_keys_str_mv |
AT chiayenliew structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT chuchunyen structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT jienlianchen structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT shangtingtsai structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT sujeetpawar structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT chungyiwu structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry AT chikungni structuralidentificationofnglycanisomersusinglogicallyderivedsequencetandemmassspectrometry |
_version_ |
1718385217003061248 |