Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with re...
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Nature Portfolio
2018
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oai:doaj.org-article:82548d3468ae4110b6b302b903b227422021-12-02T12:31:56ZElectrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite10.1038/s41598-018-25196-z2045-2322https://doaj.org/article/82548d3468ae4110b6b302b903b227422018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25196-zhttps://doaj.org/toc/2045-2322Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM.Zheng WeiYanchun WangJunping ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-8 (2018) |
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Medicine R Science Q Zheng Wei Yanchun Wang Junping Zhang Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
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Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM. |
format |
article |
author |
Zheng Wei Yanchun Wang Junping Zhang |
author_facet |
Zheng Wei Yanchun Wang Junping Zhang |
author_sort |
Zheng Wei |
title |
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
title_short |
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
title_full |
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
title_fullStr |
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
title_full_unstemmed |
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite |
title_sort |
electrochemical detection of ngf using a reduced graphene oxide- titanium nitride nanocomposite |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/82548d3468ae4110b6b302b903b22742 |
work_keys_str_mv |
AT zhengwei electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite AT yanchunwang electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite AT junpingzhang electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite |
_version_ |
1718394224614834176 |