Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite

Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with re...

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Autores principales: Zheng Wei, Yanchun Wang, Junping Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/82548d3468ae4110b6b302b903b22742
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spelling oai:doaj.org-article:82548d3468ae4110b6b302b903b227422021-12-02T12:31:56ZElectrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite10.1038/s41598-018-25196-z2045-2322https://doaj.org/article/82548d3468ae4110b6b302b903b227422018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25196-zhttps://doaj.org/toc/2045-2322Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM.Zheng WeiYanchun WangJunping ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Zheng Wei
Yanchun Wang
Junping Zhang
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
description Abstract There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM.
format article
author Zheng Wei
Yanchun Wang
Junping Zhang
author_facet Zheng Wei
Yanchun Wang
Junping Zhang
author_sort Zheng Wei
title Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_short Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_full Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_fullStr Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_full_unstemmed Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_sort electrochemical detection of ngf using a reduced graphene oxide- titanium nitride nanocomposite
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/82548d3468ae4110b6b302b903b22742
work_keys_str_mv AT zhengwei electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite
AT yanchunwang electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite
AT junpingzhang electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite
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