Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation

Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation

Abstract Atopic dermatitis (AD) often presents more severely in African Americans (AAs) and with greater involvement of extensor areas. To investigate immune signatures of AD in AAs with moderate to severe pruritus, lesional and non-lesional punch biopsies were taken from AA patients along with age-...

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Autores principales: Shannon Wongvibulsin, Nishadh Sutaria, Suraj Kannan, Martin Prince Alphonse, Micah Belzberg, Kyle A. Williams, Isabelle D. Brown, Justin Choi, Youkyung Sophie Roh, Thomas Pritchard, Raveena Khanna, Amarachi C. Eseonu, Jaroslaw Jedrych, Carly Dillen, Madan M. Kwatra, Anna L. Chien, Nathan Archer, Luis A. Garza, Xinzhong Dong, Sewon Kang, Shawn G. Kwatra
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/82598be293ef423d9b1d4aa391ce6e81
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