Genome-wide identification and differential analysis of translational initiation

Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data.

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Autores principales: Peng Zhang, Dandan He, Yi Xu, Jiakai Hou, Bih-Fang Pan, Yunfei Wang, Tao Liu, Christel M. Davis, Erik A. Ehli, Lin Tan, Feng Zhou, Jian Hu, Yonghao Yu, Xi Chen, Tuan M. Nguyen, Jeffrey M. Rosen, David H. Hawke, Zhe Ji, Yiwen Chen
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/825c960c001f405889d594142c4c5f57
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spelling oai:doaj.org-article:825c960c001f405889d594142c4c5f572021-12-02T14:42:08ZGenome-wide identification and differential analysis of translational initiation10.1038/s41467-017-01981-82041-1723https://doaj.org/article/825c960c001f405889d594142c4c5f572017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01981-8https://doaj.org/toc/2041-1723Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data.Peng ZhangDandan HeYi XuJiakai HouBih-Fang PanYunfei WangTao LiuChristel M. DavisErik A. EhliLin TanFeng ZhouJian HuYonghao YuXi ChenTuan M. NguyenJeffrey M. RosenDavid H. HawkeZhe JiYiwen ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Peng Zhang
Dandan He
Yi Xu
Jiakai Hou
Bih-Fang Pan
Yunfei Wang
Tao Liu
Christel M. Davis
Erik A. Ehli
Lin Tan
Feng Zhou
Jian Hu
Yonghao Yu
Xi Chen
Tuan M. Nguyen
Jeffrey M. Rosen
David H. Hawke
Zhe Ji
Yiwen Chen
Genome-wide identification and differential analysis of translational initiation
description Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data.
format article
author Peng Zhang
Dandan He
Yi Xu
Jiakai Hou
Bih-Fang Pan
Yunfei Wang
Tao Liu
Christel M. Davis
Erik A. Ehli
Lin Tan
Feng Zhou
Jian Hu
Yonghao Yu
Xi Chen
Tuan M. Nguyen
Jeffrey M. Rosen
David H. Hawke
Zhe Ji
Yiwen Chen
author_facet Peng Zhang
Dandan He
Yi Xu
Jiakai Hou
Bih-Fang Pan
Yunfei Wang
Tao Liu
Christel M. Davis
Erik A. Ehli
Lin Tan
Feng Zhou
Jian Hu
Yonghao Yu
Xi Chen
Tuan M. Nguyen
Jeffrey M. Rosen
David H. Hawke
Zhe Ji
Yiwen Chen
author_sort Peng Zhang
title Genome-wide identification and differential analysis of translational initiation
title_short Genome-wide identification and differential analysis of translational initiation
title_full Genome-wide identification and differential analysis of translational initiation
title_fullStr Genome-wide identification and differential analysis of translational initiation
title_full_unstemmed Genome-wide identification and differential analysis of translational initiation
title_sort genome-wide identification and differential analysis of translational initiation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/825c960c001f405889d594142c4c5f57
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