Genome-wide identification and differential analysis of translational initiation
Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/825c960c001f405889d594142c4c5f57 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:825c960c001f405889d594142c4c5f57 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:825c960c001f405889d594142c4c5f572021-12-02T14:42:08ZGenome-wide identification and differential analysis of translational initiation10.1038/s41467-017-01981-82041-1723https://doaj.org/article/825c960c001f405889d594142c4c5f572017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01981-8https://doaj.org/toc/2041-1723Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data.Peng ZhangDandan HeYi XuJiakai HouBih-Fang PanYunfei WangTao LiuChristel M. DavisErik A. EhliLin TanFeng ZhouJian HuYonghao YuXi ChenTuan M. NguyenJeffrey M. RosenDavid H. HawkeZhe JiYiwen ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Peng Zhang Dandan He Yi Xu Jiakai Hou Bih-Fang Pan Yunfei Wang Tao Liu Christel M. Davis Erik A. Ehli Lin Tan Feng Zhou Jian Hu Yonghao Yu Xi Chen Tuan M. Nguyen Jeffrey M. Rosen David H. Hawke Zhe Ji Yiwen Chen Genome-wide identification and differential analysis of translational initiation |
description |
Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame prediction from different types of ribosome profiling data. |
format |
article |
author |
Peng Zhang Dandan He Yi Xu Jiakai Hou Bih-Fang Pan Yunfei Wang Tao Liu Christel M. Davis Erik A. Ehli Lin Tan Feng Zhou Jian Hu Yonghao Yu Xi Chen Tuan M. Nguyen Jeffrey M. Rosen David H. Hawke Zhe Ji Yiwen Chen |
author_facet |
Peng Zhang Dandan He Yi Xu Jiakai Hou Bih-Fang Pan Yunfei Wang Tao Liu Christel M. Davis Erik A. Ehli Lin Tan Feng Zhou Jian Hu Yonghao Yu Xi Chen Tuan M. Nguyen Jeffrey M. Rosen David H. Hawke Zhe Ji Yiwen Chen |
author_sort |
Peng Zhang |
title |
Genome-wide identification and differential analysis of translational initiation |
title_short |
Genome-wide identification and differential analysis of translational initiation |
title_full |
Genome-wide identification and differential analysis of translational initiation |
title_fullStr |
Genome-wide identification and differential analysis of translational initiation |
title_full_unstemmed |
Genome-wide identification and differential analysis of translational initiation |
title_sort |
genome-wide identification and differential analysis of translational initiation |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/825c960c001f405889d594142c4c5f57 |
work_keys_str_mv |
AT pengzhang genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT dandanhe genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT yixu genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT jiakaihou genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT bihfangpan genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT yunfeiwang genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT taoliu genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT christelmdavis genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT erikaehli genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT lintan genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT fengzhou genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT jianhu genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT yonghaoyu genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT xichen genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT tuanmnguyen genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT jeffreymrosen genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT davidhhawke genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT zheji genomewideidentificationanddifferentialanalysisoftranslationalinitiation AT yiwenchen genomewideidentificationanddifferentialanalysisoftranslationalinitiation |
_version_ |
1718389761959264256 |