Identification of key structural features of phosphate and thiophosphate tricyclic coumarin analogs as STS inhibitors
Steroidal sulfatase (STS) is a group of arylsulfatase C enzymes that are involved in the metabolism of steroids. The increase in the circulation of the steroidogenic hormone Estradiol (E2) is responsible for causing breast cancer. Therefore, inhibitors of STS are proved to be an attractive target in...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/825cfee1c5534b2584b2b81403b29e15 |
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