Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases

Abstract Background Endoscopic negative pressure therapy is a novel and successful treatment method for a variety of gastrointestinal leaks. This therapy mode has been frequently described for rectal and esophageal leakages. Duodenal diverticular perforations are rare but life-threatening events. Th...

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Autores principales:	Dörte Wichmann, Kai Tobias Jansen, Flurina Onken, Dietmar Stüker, Emanuel Zerabruck, Christoph R. Werner, Can Yurttas, Karolin Thiel, Alfred Königsrainer, Markus Quante
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Duodenal diverticulum perforation Endoscopic negative pressure therapy Endoscopic vacuum therapy Spontaneous duodenal perforation Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/82609bdaa8774ebea73ab26248e2db32
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spelling	oai:doaj.org-article:82609bdaa8774ebea73ab26248e2db322021-11-28T12:14:54ZEndoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases10.1186/s12876-021-02018-71471-230Xhttps://doaj.org/article/82609bdaa8774ebea73ab26248e2db322021-11-01T00:00:00Zhttps://doi.org/10.1186/s12876-021-02018-7https://doaj.org/toc/1471-230XAbstract Background Endoscopic negative pressure therapy is a novel and successful treatment method for a variety of gastrointestinal leaks. This therapy mode has been frequently described for rectal and esophageal leakages. Duodenal diverticular perforations are rare but life-threatening events. The early diagnosis of duodenal diverticular perforation is often complicated by inconclusive symptoms. This is the first report about endoscopic negative pressure therapy in patients with perforated duodenal diverticula. Case presentation We present two cases of duodenal diverticula perforations treated with endoscopic negative pressure therapy as stand-alone treatment. Start of symptoms varied from one to three days before hospital admission. Early sectional imaging led to the diagnosis of duodenal diverticular perforation. Both patients were treated with endoluminal endoscopic negative pressure therapy with simultaneous feeding option. Three respective changes of the suction device were performed. Both patients were treated with antibiotics and antimycotics during their hospital stay and be discharged from hospital after 20 days. Conclusions This is the first description of successful stand-alone treatment by endoscopic negative pressure therapy in two patients with perforated duodenal diverticulum. We thus strongly recommend to attempt interventional therapy with endoluminal endoscopic negative pressure therapy in patients with duodenal diverticular perforations upfront to surgery.Dörte WichmannKai Tobias JansenFlurina OnkenDietmar StükerEmanuel ZerabruckChristoph R. WernerCan YurttasKarolin ThielAlfred KönigsrainerMarkus QuanteBMCarticleDuodenal diverticulum perforationEndoscopic negative pressure therapyEndoscopic vacuum therapySpontaneous duodenal perforationDiseases of the digestive system. GastroenterologyRC799-869ENBMC Gastroenterology, Vol 21, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Duodenal diverticulum perforation Endoscopic negative pressure therapy Endoscopic vacuum therapy Spontaneous duodenal perforation Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Duodenal diverticulum perforation Endoscopic negative pressure therapy Endoscopic vacuum therapy Spontaneous duodenal perforation Diseases of the digestive system. Gastroenterology RC799-869 Dörte Wichmann Kai Tobias Jansen Flurina Onken Dietmar Stüker Emanuel Zerabruck Christoph R. Werner Can Yurttas Karolin Thiel Alfred Königsrainer Markus Quante Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
description	Abstract Background Endoscopic negative pressure therapy is a novel and successful treatment method for a variety of gastrointestinal leaks. This therapy mode has been frequently described for rectal and esophageal leakages. Duodenal diverticular perforations are rare but life-threatening events. The early diagnosis of duodenal diverticular perforation is often complicated by inconclusive symptoms. This is the first report about endoscopic negative pressure therapy in patients with perforated duodenal diverticula. Case presentation We present two cases of duodenal diverticula perforations treated with endoscopic negative pressure therapy as stand-alone treatment. Start of symptoms varied from one to three days before hospital admission. Early sectional imaging led to the diagnosis of duodenal diverticular perforation. Both patients were treated with endoluminal endoscopic negative pressure therapy with simultaneous feeding option. Three respective changes of the suction device were performed. Both patients were treated with antibiotics and antimycotics during their hospital stay and be discharged from hospital after 20 days. Conclusions This is the first description of successful stand-alone treatment by endoscopic negative pressure therapy in two patients with perforated duodenal diverticulum. We thus strongly recommend to attempt interventional therapy with endoluminal endoscopic negative pressure therapy in patients with duodenal diverticular perforations upfront to surgery.
format	article
author	Dörte Wichmann Kai Tobias Jansen Flurina Onken Dietmar Stüker Emanuel Zerabruck Christoph R. Werner Can Yurttas Karolin Thiel Alfred Königsrainer Markus Quante
author_facet	Dörte Wichmann Kai Tobias Jansen Flurina Onken Dietmar Stüker Emanuel Zerabruck Christoph R. Werner Can Yurttas Karolin Thiel Alfred Königsrainer Markus Quante
author_sort	Dörte Wichmann
title	Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
title_short	Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
title_full	Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
title_fullStr	Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
title_full_unstemmed	Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
title_sort	endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
publisher	BMC
publishDate	2021
url	https://doaj.org/article/82609bdaa8774ebea73ab26248e2db32
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Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases

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