Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone

Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor ci...

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Autores principales: Douglas K. Reilly, Emily J. McGlame, Elke Vandewyer, Annalise N. Robidoux, Caroline S. Muirhead, Haylea T. Northcott, William Joyce, Mark J. Alkema, Robert J. Gegear, Isabel Beets, Jagan Srinivasan
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8262872adf0d4433971f18f2c5029f4e
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spelling oai:doaj.org-article:8262872adf0d4433971f18f2c5029f4e2021-12-02T16:38:24ZDistinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone10.1038/s42003-021-02547-72399-3642https://doaj.org/article/8262872adf0d4433971f18f2c5029f4e2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02547-7https://doaj.org/toc/2399-3642Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor circuitries.Douglas K. ReillyEmily J. McGlameElke VandewyerAnnalise N. RobidouxCaroline S. MuirheadHaylea T. NorthcottWilliam JoyceMark J. AlkemaRobert J. GegearIsabel BeetsJagan SrinivasanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Douglas K. Reilly
Emily J. McGlame
Elke Vandewyer
Annalise N. Robidoux
Caroline S. Muirhead
Haylea T. Northcott
William Joyce
Mark J. Alkema
Robert J. Gegear
Isabel Beets
Jagan Srinivasan
Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
description Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor circuitries.
format article
author Douglas K. Reilly
Emily J. McGlame
Elke Vandewyer
Annalise N. Robidoux
Caroline S. Muirhead
Haylea T. Northcott
William Joyce
Mark J. Alkema
Robert J. Gegear
Isabel Beets
Jagan Srinivasan
author_facet Douglas K. Reilly
Emily J. McGlame
Elke Vandewyer
Annalise N. Robidoux
Caroline S. Muirhead
Haylea T. Northcott
William Joyce
Mark J. Alkema
Robert J. Gegear
Isabel Beets
Jagan Srinivasan
author_sort Douglas K. Reilly
title Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
title_short Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
title_full Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
title_fullStr Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
title_full_unstemmed Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
title_sort distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8262872adf0d4433971f18f2c5029f4e
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