Colorectal cancer development and advances in screening

Karen Simon Ventura County Gastroenterology Medical Group, Inc., Camarillo, CA, USA Abstract: Most colon tumors develop via a multistep process involving a series of histological, morphological, and genetic changes that accumulate over time. This has allowed for screening and detection of early-st...

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Autor principal:	Simon K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	colorectal cancer DNA test polyps screening Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/8272a664bdbb434eba8933b440e38f8f
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id	oai:doaj.org-article:8272a664bdbb434eba8933b440e38f8f
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spelling	oai:doaj.org-article:8272a664bdbb434eba8933b440e38f8f2021-12-02T05:03:25ZColorectal cancer development and advances in screening1178-1998https://doaj.org/article/8272a664bdbb434eba8933b440e38f8f2016-07-01T00:00:00Zhttps://www.dovepress.com/colorectal-cancer-development-and-advances-in-screening-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Karen Simon Ventura County Gastroenterology Medical Group, Inc., Camarillo, CA, USA Abstract: Most colon tumors develop via a multistep process involving a series of histological, morphological, and genetic changes that accumulate over time. This has allowed for screening and detection of early-stage precancerous polyps before they become cancerous in individuals at average risk for colorectal cancer (CRC), which may lead to substantial decreases in the incidence of CRC. Despite the known benefits of early screening, CRC remains the second leading cause of cancer-related deaths in the United States. Hence, it is important for health care providers to have an understanding of the risk factors for CRC and various stages of disease development in order to recommend appropriate screening strategies. This article provides an overview of the histological/molecular changes that characterize the development of CRC. It describes the available CRC screening methods and their advantages and limitations and highlights the stages of CRC development in which each screening method is most effective. Keywords: colorectal cancer, DNA test, polyps, screeningSimon KDove Medical Pressarticlecolorectal cancerDNA testpolypsscreeningGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 967-976 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	colorectal cancer DNA test polyps screening Geriatrics RC952-954.6
spellingShingle	colorectal cancer DNA test polyps screening Geriatrics RC952-954.6 Simon K Colorectal cancer development and advances in screening
description	Karen Simon Ventura County Gastroenterology Medical Group, Inc., Camarillo, CA, USA Abstract: Most colon tumors develop via a multistep process involving a series of histological, morphological, and genetic changes that accumulate over time. This has allowed for screening and detection of early-stage precancerous polyps before they become cancerous in individuals at average risk for colorectal cancer (CRC), which may lead to substantial decreases in the incidence of CRC. Despite the known benefits of early screening, CRC remains the second leading cause of cancer-related deaths in the United States. Hence, it is important for health care providers to have an understanding of the risk factors for CRC and various stages of disease development in order to recommend appropriate screening strategies. This article provides an overview of the histological/molecular changes that characterize the development of CRC. It describes the available CRC screening methods and their advantages and limitations and highlights the stages of CRC development in which each screening method is most effective. Keywords: colorectal cancer, DNA test, polyps, screening
format	article
author	Simon K
author_facet	Simon K
author_sort	Simon K
title	Colorectal cancer development and advances in screening
title_short	Colorectal cancer development and advances in screening
title_full	Colorectal cancer development and advances in screening
title_fullStr	Colorectal cancer development and advances in screening
title_full_unstemmed	Colorectal cancer development and advances in screening
title_sort	colorectal cancer development and advances in screening
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/8272a664bdbb434eba8933b440e38f8f
work_keys_str_mv	AT simonk colorectalcancerdevelopmentandadvancesinscreening
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Colorectal cancer development and advances in screening

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